Population studies on three Native Alaska population groups using STR loci

Bruce Budowle, Abirami Chidambaram, Leanne Strickland, Chris W. Beheim, George M. Taft, Ranajit Chakraborty

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19 Scopus citations


Allele distributions for 13 short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, CSF1PO and D16S539 were determined for three Native Alaskan population groups - Athabaskans, Inupiats, and Yupiks. Although genetic diversity is lower in the Native Alaskan populations compared with Caucasians and Africans, almost all loci are highly polymorphic in all three Native Alaskan groups. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Only two examples of detectable departures from HWE out of 39 locus-population tests performed were observed based on the exact test (Yupik, D8S1179, P=0.030; Yupik, D5S818, P=0.016). The FST estimate overall 13 STR loci is 0.0309 for the Native Alaskan populations. Based on a genetic distance measure, Athabaskans are more closely related to Apaches and Navajos (all of the same linguistic group) than the other Native Alaskan groups. The FST estimate for Athabaskans, Apaches and Navajos is 0.0180 and for Inupiats and Yupiks is 0.0167. The allele frequency data can be used for estimating DNA profile frequencies for Native Americans residing in Alaska.

Original languageEnglish
Pages (from-to)51-57
Number of pages7
JournalForensic Science International
Issue number1
StatePublished - 10 Sep 2002


  • Alaska native population
  • Allele frequency
  • AmpFlSTR Profiler Plus and AmpFlSTR Cofiler
  • Athabaskan
  • Eskimo
  • Genetic profile
  • Inupiat
  • Population genetics
  • Short tandem repeats (STRs)
  • Yupik


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