Population genetics and forensic efficiency data of 4 AMPFLP's

S. Rand, C. Puers, K. Skowasch, P. Wiegand, B. Budowle, B. Brinkmann

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Abstract

Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.

Original languageEnglish
Pages (from-to)329-333
Number of pages5
JournalInternational journal of legal medicine
Volume104
Issue number6
DOIs
StatePublished - 1 Nov 1992

Keywords

  • AMPFLP's
  • Allele frequencies
  • Discrimination index
  • Hardy-Weinberg equilibrium
  • PCR

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