Population genetics and forensic efficiency data of 4 AMPFLP's

S. Rand; C. Puers; K. Skowasch; P. Wiegand; B. Budowle; B. Brinkmann

doi:10.1007/BF01369552

Population genetics and forensic efficiency data of 4 AMPFLP's

S. Rand, C. Puers, K. Skowasch, P. Wiegand, B. Budowle, B. Brinkmann

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Abstract

Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10^-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.

Original language	English
Pages (from-to)	329-333
Number of pages	5
Journal	International journal of legal medicine
Volume	104
Issue number	6
DOIs	https://doi.org/10.1007/BF01369552
State	Published - 1 Nov 1992

Keywords

AMPFLP's
Allele frequencies
Discrimination index
Hardy-Weinberg equilibrium
PCR

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10.1007/BF01369552

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title = "Population genetics and forensic efficiency data of 4 AMPFLP's",

abstract = "Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.",

keywords = "AMPFLP's, Allele frequencies, Discrimination index, Hardy-Weinberg equilibrium, PCR",

author = "S. Rand and C. Puers and K. Skowasch and P. Wiegand and B. Budowle and B. Brinkmann",

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T1 - Population genetics and forensic efficiency data of 4 AMPFLP's

AU - Rand, S.

AU - Puers, C.

AU - Skowasch, K.

AU - Wiegand, P.

AU - Budowle, B.

AU - Brinkmann, B.

PY - 1992/11/1

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N2 - Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.

AB - Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.

KW - AMPFLP's

KW - Allele frequencies

KW - Discrimination index

KW - Hardy-Weinberg equilibrium

KW - PCR

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Population genetics and forensic efficiency data of 4 AMPFLP's

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Keywords

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