Abstract
Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5 · 10-4. The HardyWeinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.
Original language | English |
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Pages (from-to) | 329-333 |
Number of pages | 5 |
Journal | International journal of legal medicine |
Volume | 104 |
Issue number | 6 |
DOIs | |
State | Published - 1 Nov 1992 |
Keywords
- AMPFLP's
- Allele frequencies
- Discrimination index
- Hardy-Weinberg equilibrium
- PCR