Polymorphism studies of four miniSTR loci for three ethnic populations in Singapore

Rita Y.Y. Yong; Linda S.H. Gan; Mike D. Coble; Eric P.H. Yap

doi:10.1016/j.legalmed.2007.01.008

Polymorphism studies of four miniSTR loci for three ethnic populations in Singapore

Rita Y.Y. Yong, Linda S.H. Gan, Mike D. Coble, Eric P.H. Yap

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR amplicon sizes. This study constructed a partial miniSGM panel and investigated the performance of four miniSTR loci, D2S1338, D16S539, D18S51 and FGA, in three ethnic populations residing in Singapore. The suitability of the miniSTR primers for Singapore populations was assessed for loci D16S539, D18S51 and FGA.

Original language	English
Pages (from-to)	278-281
Number of pages	4
Journal	Legal Medicine
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/j.legalmed.2007.01.008
State	Published - Sep 2007

Keywords

Allele frequencies
Concordance
Malay and Indian
MiniSGM
MiniSTR
Population data
Singapore Chinese

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10.1016/j.legalmed.2007.01.008

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title = "Polymorphism studies of four miniSTR loci for three ethnic populations in Singapore",

abstract = "MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR amplicon sizes. This study constructed a partial miniSGM panel and investigated the performance of four miniSTR loci, D2S1338, D16S539, D18S51 and FGA, in three ethnic populations residing in Singapore. The suitability of the miniSTR primers for Singapore populations was assessed for loci D16S539, D18S51 and FGA.",

keywords = "Allele frequencies, Concordance, Malay and Indian, MiniSGM, MiniSTR, Population data, Singapore Chinese",

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AU - Yap, Eric P.H.

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Y1 - 2007/9

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AB - MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR amplicon sizes. This study constructed a partial miniSGM panel and investigated the performance of four miniSTR loci, D2S1338, D16S539, D18S51 and FGA, in three ethnic populations residing in Singapore. The suitability of the miniSTR primers for Singapore populations was assessed for loci D16S539, D18S51 and FGA.

KW - Allele frequencies

KW - Concordance

KW - Malay and Indian

KW - MiniSGM

KW - MiniSTR

KW - Population data

KW - Singapore Chinese

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JO - Legal Medicine

JF - Legal Medicine

IS - 5

ER -

Polymorphism studies of four miniSTR loci for three ethnic populations in Singapore

Abstract

Keywords

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