Photophysical properties and detection of Valrubicin on plasmonic platforms

Anna Synak; Elżbieta Szczepańska; Beata Grobelna; Joanna Gondek; Michał Mońka; Ignacy Gryczynski; Piotr Bojarski

doi:10.1016/j.dyepig.2018.12.032

Photophysical properties and detection of Valrubicin on plasmonic platforms

Anna Synak, Elżbieta Szczepańska, Beata Grobelna, Joanna Gondek, Michał Mońka, Ignacy Gryczynski, Piotr Bojarski

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Plasmonic platforms allow reliable visualization and detection of Valrubicin, a medically important chemotherapeutic molecule. Different plasmonic platforms constructed with silver nanoparticles (AgNps) or core-shell nanostructures (Ag@SiO ₂ ) deposited and arranged on semitransparent silver/gold mirrors were exploited in the study using various spectroscopic and microscopic techniques. It is shown that the developed new plasmonic platform provides new quality of sensitive detection of the examined anticancer drug. Due to the interactions of the specimen with surface plasmons the brightness achievable in microscopic imaging of Valrubicin can be enhanced even 50 times for platforms containing core-shell nanoparticles.

Original language	English
Pages (from-to)	623-627
Number of pages	5
Journal	Dyes and Pigments
Volume	163
DOIs	https://doi.org/10.1016/j.dyepig.2018.12.032
State	Published - Apr 2019

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10.1016/j.dyepig.2018.12.032

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title = "Photophysical properties and detection of Valrubicin on plasmonic platforms",

abstract = " Plasmonic platforms allow reliable visualization and detection of Valrubicin, a medically important chemotherapeutic molecule. Different plasmonic platforms constructed with silver nanoparticles (AgNps) or core-shell nanostructures (Ag@SiO 2 ) deposited and arranged on semitransparent silver/gold mirrors were exploited in the study using various spectroscopic and microscopic techniques. It is shown that the developed new plasmonic platform provides new quality of sensitive detection of the examined anticancer drug. Due to the interactions of the specimen with surface plasmons the brightness achievable in microscopic imaging of Valrubicin can be enhanced even 50 times for platforms containing core-shell nanoparticles. ",

author = "Anna Synak and El{\.z}bieta Szczepa{\'n}ska and Beata Grobelna and Joanna Gondek and Micha{\l} Mo{\'n}ka and Ignacy Gryczynski and Piotr Bojarski",

note = "Funding Information: This research were supported by the grants: 2017/01/X/ST4/00542 (A.S.) and 2015/17/B/ST5/03143 (P.B.; B.G.) financed by National Science Centre. Funding Information: This research were supported by the grants: 2017/01/X/ST4/00542 (A.S.) and 2015/17/B/ST5/03143 (P.B.; B.G.) financed by National Science Centre . Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

year = "2019",

month = apr,

doi = "10.1016/j.dyepig.2018.12.032",

language = "English",

volume = "163",

pages = "623--627",

journal = "Dyes and Pigments",

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T1 - Photophysical properties and detection of Valrubicin on plasmonic platforms

AU - Synak, Anna

AU - Szczepańska, Elżbieta

AU - Grobelna, Beata

AU - Gondek, Joanna

AU - Mońka, Michał

AU - Gryczynski, Ignacy

AU - Bojarski, Piotr

N1 - Funding Information: This research were supported by the grants: 2017/01/X/ST4/00542 (A.S.) and 2015/17/B/ST5/03143 (P.B.; B.G.) financed by National Science Centre. Funding Information: This research were supported by the grants: 2017/01/X/ST4/00542 (A.S.) and 2015/17/B/ST5/03143 (P.B.; B.G.) financed by National Science Centre . Publisher Copyright: © 2018 Elsevier Ltd Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/4

Y1 - 2019/4

N2 - Plasmonic platforms allow reliable visualization and detection of Valrubicin, a medically important chemotherapeutic molecule. Different plasmonic platforms constructed with silver nanoparticles (AgNps) or core-shell nanostructures (Ag@SiO 2 ) deposited and arranged on semitransparent silver/gold mirrors were exploited in the study using various spectroscopic and microscopic techniques. It is shown that the developed new plasmonic platform provides new quality of sensitive detection of the examined anticancer drug. Due to the interactions of the specimen with surface plasmons the brightness achievable in microscopic imaging of Valrubicin can be enhanced even 50 times for platforms containing core-shell nanoparticles.

AB - Plasmonic platforms allow reliable visualization and detection of Valrubicin, a medically important chemotherapeutic molecule. Different plasmonic platforms constructed with silver nanoparticles (AgNps) or core-shell nanostructures (Ag@SiO 2 ) deposited and arranged on semitransparent silver/gold mirrors were exploited in the study using various spectroscopic and microscopic techniques. It is shown that the developed new plasmonic platform provides new quality of sensitive detection of the examined anticancer drug. Due to the interactions of the specimen with surface plasmons the brightness achievable in microscopic imaging of Valrubicin can be enhanced even 50 times for platforms containing core-shell nanoparticles.

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VL - 163

SP - 623

EP - 627

JO - Dyes and Pigments

JF - Dyes and Pigments

ER -

Photophysical properties and detection of Valrubicin on plasmonic platforms

Abstract

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