Phosphatidylinositol 3-kinase inhibitors reveal a unique mechanism of enhancing insulin secretion in 832/13 rat insulinoma cells

Medicine & Life Sciences

• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 51%
• Action Potentials 26%
• Calcium 9%
• Enzyme Inhibitors 16%
• Glucose 9%
• Hyperinsulinism 15%
• In Vitro Techniques 6%
• Insulin 19%
• Insulin Resistance 11%
• Insulin Secretion 57%
• Insulinoma 73%
• Membrane Potentials 14%
• Phosphatidylinositol 3-Kinase 58%
• Phosphorylation 9%
• Potassium Channels 16%
• Type 2 Diabetes Mellitus 10%
• Wortmannin 35%

Chemical Compounds

• Block Like Crystal 5%
• Calcium(0) 6%
• Glucose 6%
• Insulin Derivative 59%
• LY294002 45%
• Membrane Potential 9%
• Phosphatidylinositol 9%
• Phosphatidylinositol 3 Kinase Inhibitor 100%
• Resistance 5%
• Wortmannin 28%