PHENOTYPES OF THE FOURTH COMPLEMENT COMPONENT (C4) IN BLACK AMERICANS FROM THE SOUTHEASTERN UNITED STATES

B. Budowle, J. M. Roseman, R. C.P. Go, W. Louv, B. O. Barger, R. T. Acton

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

C4 is composed of two tightly linked genes (C4A and C4B) lying within the major histocompatibility complex of chromosome 6 that can be demonstrated by agarose gel electrophoresis. Seven alleles and five alleles at the C4A and C4B loci, respectively, were detected in 169 black individuals from the southeastern United States. Furthermore, the phenotypic frequencies of C4A6, C4A5, C4A4, C4B4, C4B3, and C4BQO were significantly different between black and white Americans.

Original languageEnglish
Pages (from-to)199-204
Number of pages6
JournalInternational Journal of Immunogenetics
Volume10
Issue number3
DOIs
StatePublished - Jun 1983

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