Phase I trial of continuous infusion carboplatin and etoposide in children with refractory acute leukemia: A Pediatric Oncology Group study

Keyphrases

• Etoposide 100%
• Group Studies 100%
• Carboplatin 100%
• Phase I Trial 100%
• Pediatric Oncology 100%
• Continuous Infusion 100%
• Relapsed or Refractory Acute Myeloid Leukemia 100%
• VP16 40%
• Marrow 40%
• Intravenous Infusion 40%
• Treatment Course 40%
• Complete Remission 20%
• Total Dose 20%
• Fixed-dose Combination 20%
• Dose Level 20%
• Diarrhea 20%
• Antileukemic Activity 20%
• Phase II Trial 20%
• Bleeding 20%
• Thrombocytopenia 20%
• Phase I Study 20%
• Aplasia 20%
• Partial Remission 20%
• Life-threatening Infections 20%
• Marrow Suppression 20%
• Extramedullary 20%

Medicine and Dentistry

• Etoposide 100%
• Phase I Trials 100%
• Childhood Cancer 100%
• Continuous Infusion 100%
• Carboplatin 100%
• Acute Leukemia 100%
• Intravenous Drug Administration 40%
• Bleeding 20%
• Infection 20%
• Diarrhea 20%
• Phase II Trials 20%
• Aplasia 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Etoposide 100%
• Carboplatin 100%
• Childhood Cancer 100%
• Acute Leukemia 100%
• Phase I Trials 100%
• Remission 40%
• Bleeding 20%
• Infection 20%
• Diarrhea 20%
• Phase II Trials 20%
• Aplasia 20%