Pharmacists' evaluations of the nonprescription availability of metaproterenol, cimetidine, ibuprofen, and nystatin

S. Madhavan, S. W. Schondelmeyer

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The relative importance of six switch evaluation criteria in pharmacists' evaluations of the appropriateness of switching four drugs from prescription to nonpresciption status was assessed. A questionnaire was constructed for three potential switch candidates (metaproterenol, cimetidine, and nystatin) and one already switched drug (ibuprofen 200 mg). Pharmacists were asked to judge (1) the overall appropriateness of switching these four drugs and (2) the appropriateness of switching these drugs based on the FDA switch criteria of safety, effectiveness, and labeling and two other proposed criteria: the need for oral counseling about the product and perceived market need for the product. Additionally, pharmacists were asked to rate whether they believed the study drugs would be profitable to their pharmacies if the drugs were switched to nonprescription status. A total of 1161 pharmacists were reached by the mailings, of whom 417 (34.8%) responded. Only ibuprofen 200 mg received a positive overall switch approval rating from the pharmacists; cimetidine received the lowest rating. The six evaluation criteria were tested for significant association with pharmacists' overall judgement of the appropriateness of switching each drug. The three most influential criteria were safety, labeling, and market need for the product, respectively. Profitability to the pharmacy was not significantly associated with pharmacists' overall judgement of switch appropriateness. Regression analysis identified safety, labeling, and market need as important in the evaluation of all four drugs, and pharmacists' evaluation of the relative importance of these criteria was a predictor of their overall judgement of the appropriateness of a switch. Consumer safety, not personal economic interests, most influenced pharmacists' judgement of the appropriateness of a switch from prescription to nonprescription status for four drugs.

Original languageEnglish
Pages (from-to)2486-2492
Number of pages7
JournalAmerican Journal of Hospital Pharmacy
Volume46
Issue number12
StatePublished - 1 Jan 1989

Keywords

  • Anti-inflammatory agents
  • Antifungals
  • Cimetidine
  • Classification
  • Consumers
  • Data collection
  • Drugs, nonprescription
  • Food and Drug Administration (U.S.)
  • Gastrointestinal drugs
  • Ibuprofen
  • Labeling
  • Marketing
  • Metaproterenol
  • Nystatin
  • Patient information
  • Pharmacists
  • Prescriptions
  • Professionalism
  • Profits
  • Regulati ons
  • Sympathomimetic agents
  • Toxicity

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