Perforin gene defects in familial hemophagocytic lymphohistiocytosis

Keyphrases

• Hemophagocytic Lymphohistiocytosis 100%
• Perforin Gene 100%
• Gene Defects 100%
• Perforin 60%
• Coding Region 20%
• Abnormal Cells 20%
• T Cell Activation 20%
• Macrophages 20%
• Effector Mechanisms 20%
• Missense mutation 20%
• Autosomal Recessive 20%
• Inflammatory Cytokines 20%
• Immunostaining 20%
• Immune Activation 20%
• Homozygous Nonsense mutation 20%
• Patient mutations 20%
• Lymphocytes 20%
• Cytotoxic Activity 20%
• Linkage Analysis 20%
• Lysis 20%
• Immune Disorders 20%
• Granules 20%
• Overproduction 20%
• Cellular Immune Response 20%

Immunology and Microbiology

• Perforin 100%
• Hemophagocytic Lymphohistiocytosis 100%
• Cytotoxicity 20%
• T Cell 20%
• Autosomal Recessive Inheritance 20%
• Immunostaining 20%
• Lymphocyte Culture 20%
• Macrophage 20%
• Inflammatory Cytokine 20%
• Downregulation 20%
• Missense Mutation 20%
• Nonsense Mutation 20%
• Immunity 20%
• Immune System Disorders 20%