Osteopathic Manipulative Treatment Alters Gastric Myoelectric Activity in Healthy Subjects

Edward Shadiack, Noah Jouett, Amber Van Den Raadt, Roselle Liganor, Jacob Watters, Kendi Lee Hensel, Michael L. Smith

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objectives: It is unclear whether osteopathic manipulative treatment (OMT) affects gastric myoelectric activity (GMA), an index of gastric motility. We hypothesized that OMT significantly alters power spectral density (PSD) analyses of electrogastrography (EGG) recordings, an index of GMA, compared with time control OMT. Design: GMA data were obtained from nine subjects before and after OMT and time control on separate days in a cross-over design. Fifteen-minute EGG recordings were obtained before and after each intervention and after a water challenge (WC). Percent power in the normogastric range (PPN) was estimated from PSD analyses. Absolute percent change of PPN and dominant frequency (DF) from baseline to postintervention and baseline to post-WC was computed and compared using two-way repeated-measures ANOVA. Results: OMT altered PPN versus time control (time control: 5.3% ± 1.2%; OMT: 24.5% ± 4.5%; p = 0.015). WC altered PPN compared with time control (post-time control ΔPPN: 5.3% ± 1.2%; post-drink ΔPPN: 30.3% ± 7.2%; p < 0.01). However, WC did not alter PPN with prior OMT treatment (post-OMT ΔPPN: 24.5% ± 4.5%; post-WC ΔPPN: 19.4% ± 5.6%; p = 0.47). Nevertheless, OMT reduced the rate of change for DF compared with time control (WC post-time control: 37.9% ± 7.4%; WC post-OMT: 20.0% ± 5.9%; p = 0.02). Conclusions: We conclude that (1) OMT significantly alters GMA compared with time control and that (2) OMT reduces the rate of change in the frequency response to WC within the normal frequency range of 2-4 cycles per minute, indicating a physiological effect.

Original languageEnglish
Pages (from-to)1176-1180
Number of pages5
JournalJournal of Alternative and Complementary Medicine
Volume24
Issue number12
DOIs
StatePublished - 1 Dec 2018

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Osteopathic Manipulation
Stomach
Healthy Volunteers
Water

Keywords

  • OMT
  • electrogastrography
  • gastrointestinal
  • motility
  • osteopathic

Cite this

Shadiack, Edward ; Jouett, Noah ; Van Den Raadt, Amber ; Liganor, Roselle ; Watters, Jacob ; Hensel, Kendi Lee ; Smith, Michael L. / Osteopathic Manipulative Treatment Alters Gastric Myoelectric Activity in Healthy Subjects. In: Journal of Alternative and Complementary Medicine. 2018 ; Vol. 24, No. 12. pp. 1176-1180.
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title = "Osteopathic Manipulative Treatment Alters Gastric Myoelectric Activity in Healthy Subjects",
abstract = "Objectives: It is unclear whether osteopathic manipulative treatment (OMT) affects gastric myoelectric activity (GMA), an index of gastric motility. We hypothesized that OMT significantly alters power spectral density (PSD) analyses of electrogastrography (EGG) recordings, an index of GMA, compared with time control OMT. Design: GMA data were obtained from nine subjects before and after OMT and time control on separate days in a cross-over design. Fifteen-minute EGG recordings were obtained before and after each intervention and after a water challenge (WC). Percent power in the normogastric range (PPN) was estimated from PSD analyses. Absolute percent change of PPN and dominant frequency (DF) from baseline to postintervention and baseline to post-WC was computed and compared using two-way repeated-measures ANOVA. Results: OMT altered PPN versus time control (time control: 5.3{\%} ± 1.2{\%}; OMT: 24.5{\%} ± 4.5{\%}; p = 0.015). WC altered PPN compared with time control (post-time control ΔPPN: 5.3{\%} ± 1.2{\%}; post-drink ΔPPN: 30.3{\%} ± 7.2{\%}; p < 0.01). However, WC did not alter PPN with prior OMT treatment (post-OMT ΔPPN: 24.5{\%} ± 4.5{\%}; post-WC ΔPPN: 19.4{\%} ± 5.6{\%}; p = 0.47). Nevertheless, OMT reduced the rate of change for DF compared with time control (WC post-time control: 37.9{\%} ± 7.4{\%}; WC post-OMT: 20.0{\%} ± 5.9{\%}; p = 0.02). Conclusions: We conclude that (1) OMT significantly alters GMA compared with time control and that (2) OMT reduces the rate of change in the frequency response to WC within the normal frequency range of 2-4 cycles per minute, indicating a physiological effect.",
keywords = "OMT, electrogastrography, gastrointestinal, motility, osteopathic",
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Osteopathic Manipulative Treatment Alters Gastric Myoelectric Activity in Healthy Subjects. / Shadiack, Edward; Jouett, Noah; Van Den Raadt, Amber; Liganor, Roselle; Watters, Jacob; Hensel, Kendi Lee; Smith, Michael L.

In: Journal of Alternative and Complementary Medicine, Vol. 24, No. 12, 01.12.2018, p. 1176-1180.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Osteopathic Manipulative Treatment Alters Gastric Myoelectric Activity in Healthy Subjects

AU - Shadiack, Edward

AU - Jouett, Noah

AU - Van Den Raadt, Amber

AU - Liganor, Roselle

AU - Watters, Jacob

AU - Hensel, Kendi Lee

AU - Smith, Michael L.

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N2 - Objectives: It is unclear whether osteopathic manipulative treatment (OMT) affects gastric myoelectric activity (GMA), an index of gastric motility. We hypothesized that OMT significantly alters power spectral density (PSD) analyses of electrogastrography (EGG) recordings, an index of GMA, compared with time control OMT. Design: GMA data were obtained from nine subjects before and after OMT and time control on separate days in a cross-over design. Fifteen-minute EGG recordings were obtained before and after each intervention and after a water challenge (WC). Percent power in the normogastric range (PPN) was estimated from PSD analyses. Absolute percent change of PPN and dominant frequency (DF) from baseline to postintervention and baseline to post-WC was computed and compared using two-way repeated-measures ANOVA. Results: OMT altered PPN versus time control (time control: 5.3% ± 1.2%; OMT: 24.5% ± 4.5%; p = 0.015). WC altered PPN compared with time control (post-time control ΔPPN: 5.3% ± 1.2%; post-drink ΔPPN: 30.3% ± 7.2%; p < 0.01). However, WC did not alter PPN with prior OMT treatment (post-OMT ΔPPN: 24.5% ± 4.5%; post-WC ΔPPN: 19.4% ± 5.6%; p = 0.47). Nevertheless, OMT reduced the rate of change for DF compared with time control (WC post-time control: 37.9% ± 7.4%; WC post-OMT: 20.0% ± 5.9%; p = 0.02). Conclusions: We conclude that (1) OMT significantly alters GMA compared with time control and that (2) OMT reduces the rate of change in the frequency response to WC within the normal frequency range of 2-4 cycles per minute, indicating a physiological effect.

AB - Objectives: It is unclear whether osteopathic manipulative treatment (OMT) affects gastric myoelectric activity (GMA), an index of gastric motility. We hypothesized that OMT significantly alters power spectral density (PSD) analyses of electrogastrography (EGG) recordings, an index of GMA, compared with time control OMT. Design: GMA data were obtained from nine subjects before and after OMT and time control on separate days in a cross-over design. Fifteen-minute EGG recordings were obtained before and after each intervention and after a water challenge (WC). Percent power in the normogastric range (PPN) was estimated from PSD analyses. Absolute percent change of PPN and dominant frequency (DF) from baseline to postintervention and baseline to post-WC was computed and compared using two-way repeated-measures ANOVA. Results: OMT altered PPN versus time control (time control: 5.3% ± 1.2%; OMT: 24.5% ± 4.5%; p = 0.015). WC altered PPN compared with time control (post-time control ΔPPN: 5.3% ± 1.2%; post-drink ΔPPN: 30.3% ± 7.2%; p < 0.01). However, WC did not alter PPN with prior OMT treatment (post-OMT ΔPPN: 24.5% ± 4.5%; post-WC ΔPPN: 19.4% ± 5.6%; p = 0.47). Nevertheless, OMT reduced the rate of change for DF compared with time control (WC post-time control: 37.9% ± 7.4%; WC post-OMT: 20.0% ± 5.9%; p = 0.02). Conclusions: We conclude that (1) OMT significantly alters GMA compared with time control and that (2) OMT reduces the rate of change in the frequency response to WC within the normal frequency range of 2-4 cycles per minute, indicating a physiological effect.

KW - OMT

KW - electrogastrography

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KW - osteopathic

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