Optic neuropathy in vitamin B12 deficiency

Sai Chavala, Gregory S. Kosmorsky, Mina K. Lee, Michael S. Lee

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There are many neurological manifestations of vitamin B12 deficiency. Optic neuropathy is a rare, but important, manifestation of vitamin B12 deficiency that should be suspected in patients with risk factors for malnutrition. We present a case of a 68-year-old male who presented with bilateral decreased central vision for months and was found to have a low vitamin B12 level. After a few months, his vision improved with parenteral vitamin B12 supplementation. Vitamin B12 optic neuropathy is a reversible, treatable cause of vision loss and may be a harbinger for other manifestations of the disease.

Original languageEnglish
Pages (from-to)447-448
Number of pages2
JournalEuropean Journal of Internal Medicine
Issue number6
StatePublished - 1 Oct 2005


  • Cobalamin
  • Optic neuropathy
  • Tobacco
  • Vision loss

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    Chavala, S., Kosmorsky, G. S., Lee, M. K., & Lee, M. S. (2005). Optic neuropathy in vitamin B12 deficiency. European Journal of Internal Medicine, 16(6), 447-448. https://doi.org/10.1016/j.ejim.2005.01.021