TY - JOUR
T1 - Opioid use and the presence of Alzheimer's disease and related dementias among elderly Medicare beneficiaries diagnosed with chronic pain conditions
AU - Shen, Chan
AU - Zhao, Xiaohui
AU - Dwibedi, Nilanjana
AU - Wiener, R. Constance
AU - Findley, Patricia A.
AU - Sambamoorthi, Usha
N1 - Funding Information:
Research reported in this publication was supported (Dr. Sambamoorthi) by the National Institute of General Medical Sciences of the National Institutes of Health under award number 2U54GM104942-02 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank Gary Deyter for editorial assistance.
Publisher Copyright:
© 2018
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Introduction: There is scant literature on the use of opioids among community-dwelling elderly with Alzheimer's disease and related dementias (ADRD). Methods: We adopted a retrospective, cross-sectional study design using Medicare Current Beneficiary Survey data from 2006 to 2013. The study sample included elderly community-dwelling Medicare beneficiaries who were diagnosed with chronic pain conditions and had Medicare fee-for-service plans for the entire year. We conducted bivariate χ2 test and multivariate logistic regression to examine the relationship between opioid use and ADRD status. Results: The study sample included 19,347 Medicare beneficiaries; 7.7% of them had ADRD. We found no statistically significant difference in opioid use by ADRD status in the unadjusted analysis; however, controlling for various factors, those with ADRD had lower odds of opioid use (adjusted odds ratio = 0.81, 95% confidence interval = 0.71, 0.93) than those without ADRD. Discussion: This population-based study suggests that elderly Medicare beneficiaries with ADRD and chronic pain conditions may have undertreatment of pain.
AB - Introduction: There is scant literature on the use of opioids among community-dwelling elderly with Alzheimer's disease and related dementias (ADRD). Methods: We adopted a retrospective, cross-sectional study design using Medicare Current Beneficiary Survey data from 2006 to 2013. The study sample included elderly community-dwelling Medicare beneficiaries who were diagnosed with chronic pain conditions and had Medicare fee-for-service plans for the entire year. We conducted bivariate χ2 test and multivariate logistic regression to examine the relationship between opioid use and ADRD status. Results: The study sample included 19,347 Medicare beneficiaries; 7.7% of them had ADRD. We found no statistically significant difference in opioid use by ADRD status in the unadjusted analysis; however, controlling for various factors, those with ADRD had lower odds of opioid use (adjusted odds ratio = 0.81, 95% confidence interval = 0.71, 0.93) than those without ADRD. Discussion: This population-based study suggests that elderly Medicare beneficiaries with ADRD and chronic pain conditions may have undertreatment of pain.
KW - Alzheimer's disease and related dementias
KW - Chronic pain conditions
KW - Elderly population
KW - Medicare
KW - Opioid use
UR - http://www.scopus.com/inward/record.url?scp=85057580055&partnerID=8YFLogxK
U2 - 10.1016/j.trci.2018.10.012
DO - 10.1016/j.trci.2018.10.012
M3 - Article
AN - SCOPUS:85057580055
SN - 2352-8737
VL - 4
SP - 661
EP - 668
JO - Alzheimer's and Dementia: Translational Research and Clinical Interventions
JF - Alzheimer's and Dementia: Translational Research and Clinical Interventions
ER -