On the rate of cholesterol esterification in cord blood serum

Andras G. Lacko, Harold L. Rutenberg, Louis A. Soloff

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26 Citations (Scopus)

Abstract

Cholesterol esterification was studied in adult and cord serum by measureing the initial rate of lecithin-cholesterol acyl transferase (LCAT) activity. Cord serum had about one-third as much free and esterified cholesterol and about one-half as much LCAT as adult serum. When the adult LCAT activities are plotted against the individual's serum free cholesterol levels a straight line relationship results (0.101±.005% cholesterol esterified per min). Cord serum LCAT activities (.135±.0407% cholesterol esterified per min) in the main fall above the adult line. Our results show that cord serum can esterify cholesterol at a rate equal to or higher than adult serum when the LCAT activity is related to the amount of serum free cholesterol present.

Original languageEnglish
Pages (from-to)426-429
Number of pages4
JournalLipids
Volume7
Issue number6
DOIs
StatePublished - 1 Jun 1972

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Esterification
Fetal Blood
Blood
Cholesterol
Serum
Lecithins
Transferases

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Lacko, Andras G. ; Rutenberg, Harold L. ; Soloff, Louis A. / On the rate of cholesterol esterification in cord blood serum. In: Lipids. 1972 ; Vol. 7, No. 6. pp. 426-429.
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On the rate of cholesterol esterification in cord blood serum. / Lacko, Andras G.; Rutenberg, Harold L.; Soloff, Louis A.

In: Lipids, Vol. 7, No. 6, 01.06.1972, p. 426-429.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Soloff, Louis A.

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