On the interpretation and potential diagnostic value of the measurements related to lecithin:cholesterol acyltransferase activity

Andras G. Lacko

doi:10.1016/S0009-9120(76)80060-4

On the interpretation and potential diagnostic value of the measurements related to lecithin:cholesterol acyltransferase activity

Andras G. Lacko

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

At least one reliable method is available for measuring LCAT activity in human subjects⁽²⁵⁾, and this assay may help to probe even subtle changes in plasma lipids and lipoproteins. Since plasma lipids and lipoproteins are known to be present in abnormal amounts in a large number of metabolic diseases, the method of measuring the rate of cholesterol esterification in plasma could assume a substantial role in the diagnosis and (or) monitoring of treatment of pathologic states.

Original language	English
Pages (from-to)	212-215
Number of pages	4
Journal	Clinical Biochemistry
Volume	9
Issue number	C
DOIs	https://doi.org/10.1016/S0009-9120(76)80060-4
State	Published - 1976

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title = "On the interpretation and potential diagnostic value of the measurements related to lecithin:cholesterol acyltransferase activity",

abstract = "At least one reliable method is available for measuring LCAT activity in human subjects(25), and this assay may help to probe even subtle changes in plasma lipids and lipoproteins. Since plasma lipids and lipoproteins are known to be present in abnormal amounts in a large number of metabolic diseases, the method of measuring the rate of cholesterol esterification in plasma could assume a substantial role in the diagnosis and (or) monitoring of treatment of pathologic states.",

author = "Lacko, {Andras G.}",

note = "Funding Information: The author is grateful to Louis A. Soloff, K. G. Varma and H. L. Rutenberg for many helpful discussions, and to K. Dorr for excellent secretarial assistance. This work was supported by NIH grant HL-19142.",

year = "1976",

doi = "10.1016/S0009-9120(76)80060-4",

language = "English",

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pages = "212--215",

journal = "Clinical Biochemistry",

issn = "0009-9120",

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T1 - On the interpretation and potential diagnostic value of the measurements related to lecithin:cholesterol acyltransferase activity

AU - Lacko, Andras G.

N1 - Funding Information: The author is grateful to Louis A. Soloff, K. G. Varma and H. L. Rutenberg for many helpful discussions, and to K. Dorr for excellent secretarial assistance. This work was supported by NIH grant HL-19142.

PY - 1976

Y1 - 1976

N2 - At least one reliable method is available for measuring LCAT activity in human subjects(25), and this assay may help to probe even subtle changes in plasma lipids and lipoproteins. Since plasma lipids and lipoproteins are known to be present in abnormal amounts in a large number of metabolic diseases, the method of measuring the rate of cholesterol esterification in plasma could assume a substantial role in the diagnosis and (or) monitoring of treatment of pathologic states.

AB - At least one reliable method is available for measuring LCAT activity in human subjects(25), and this assay may help to probe even subtle changes in plasma lipids and lipoproteins. Since plasma lipids and lipoproteins are known to be present in abnormal amounts in a large number of metabolic diseases, the method of measuring the rate of cholesterol esterification in plasma could assume a substantial role in the diagnosis and (or) monitoring of treatment of pathologic states.

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U2 - 10.1016/S0009-9120(76)80060-4

DO - 10.1016/S0009-9120(76)80060-4

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AN - SCOPUS:0017130110

SN - 0009-9120

VL - 9

SP - 212

EP - 215

JO - Clinical Biochemistry

JF - Clinical Biochemistry

IS - C

ER -

On the interpretation and potential diagnostic value of the measurements related to lecithin:cholesterol acyltransferase activity

Abstract

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