Ocular manifestations and concepts of systemic vasculitides

Victor L. Perez, Sai H. Chavala, Muna Ahmed, David Chu, Panos Zafirakis, Stefanos Baltatzis, Vicente Ocampo, C. Stephen Foster

Research output: Contribution to journalReview article

41 Scopus citations

Abstract

Vasculitic disorders are relatively rare. Their etiology and pathophysiology remain enigmatic, leading to confusing nomenclature and multiple classification schemes. Untreated vasculitis can be fatal. Early diagnosis is the key to successful treatment and better prognosis. However, early diagnosis can be difficult; vasculitic conditions usually present with non-specific symptoms for a long period before clinically overt manifestations occur. Ophthalmologists should be familiar with the ocular manifestations of the vasculitic disorders because they may not only be sight-threatening, but more importantly could be the presenting manifestations of active, potentially lethal systemic disease. This review summarizes clinical and ocular manifestations of systemic vasculitic disorders. Furthermore, it discusses general concepts in diagnosis and treatment of these diseases in an effort to provide a practical framework for the ophthalmologist evaluating patients with vasculitis.

Original languageEnglish
Pages (from-to)399-418
Number of pages20
JournalSurvey of Ophthalmology
Volume49
Issue number4
DOIs
StatePublished - 1 Jul 2004

Keywords

  • Churg-Strauss syndrome
  • Henoch-Schönlein purpura
  • Kawasaki disease
  • Takayasu's arteritis
  • cutaneous leukocytoclastic angiitis
  • giant cell arteritis
  • microscopic polyangiitis
  • ocular manifestations
  • polyarteritis nodosa
  • primary vasculitis

Fingerprint Dive into the research topics of 'Ocular manifestations and concepts of systemic vasculitides'. Together they form a unique fingerprint.

  • Cite this

    Perez, V. L., Chavala, S. H., Ahmed, M., Chu, D., Zafirakis, P., Baltatzis, S., Ocampo, V., & Foster, C. S. (2004). Ocular manifestations and concepts of systemic vasculitides. Survey of Ophthalmology, 49(4), 399-418. https://doi.org/10.1016/j.survophthal.2004.04.008