TY - JOUR
T1 - Ocular Complications of Diabetes and Therapeutic Approaches
AU - Vieira-Potter, Victoria J.
AU - Karamichos, Dimitrios
AU - Lee, Darren J.
N1 - Publisher Copyright:
© 2016 Victoria J. Vieira-Potter et al.
PY - 2016
Y1 - 2016
N2 - Diabetes mellitus (DM) is a metabolic disease defined by elevated blood glucose (BG). DM is a global epidemic and the prevalence is anticipated to continue to increase. The ocular complications of DM negatively impact the quality of life and carry an extremely high economic burden. While systemic control of BG can slow the ocular complications they cannot stop them, especially if clinical symptoms are already present. With the advances in biodegradable polymers, implantable ocular devices can slowly release medication to stop, and in some cases reverse, diabetic complications in the eye. In this review we discuss the ocular complications associated with DM, the treatments available with a focus on localized treatments, and what promising treatments are on the horizon.
AB - Diabetes mellitus (DM) is a metabolic disease defined by elevated blood glucose (BG). DM is a global epidemic and the prevalence is anticipated to continue to increase. The ocular complications of DM negatively impact the quality of life and carry an extremely high economic burden. While systemic control of BG can slow the ocular complications they cannot stop them, especially if clinical symptoms are already present. With the advances in biodegradable polymers, implantable ocular devices can slowly release medication to stop, and in some cases reverse, diabetic complications in the eye. In this review we discuss the ocular complications associated with DM, the treatments available with a focus on localized treatments, and what promising treatments are on the horizon.
UR - http://www.scopus.com/inward/record.url?scp=84971430910&partnerID=8YFLogxK
U2 - 10.1155/2016/3801570
DO - 10.1155/2016/3801570
M3 - Review article
C2 - 27119078
AN - SCOPUS:84971430910
SN - 2314-6133
VL - 2016
JO - BioMed research international
JF - BioMed research international
M1 - 3801570
ER -