Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu ₁

Keyphrases

• Negative Allosteric Modulator 100%
• MGlu 100%
• Pyrrole 100%
• Cell-based 33%
• Inhibition Assay 33%
• P450 Inhibition 33%
• Drug-likeness 33%
• Protein Binding Rate 33%
• MGlu1 33%
• Isosteric Replacement 33%
• Piperazine Ring 33%
• Hit Compound 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Allosteric Modulator 100%
• Pyrrole 100%
• Protein Binding 33%
• Piperazine 33%
• Cytochrome P450 33%
• Structure Activity Relationship 33%

Medicine and Dentistry

• Allosteric Modulator 100%
• Pyrrole 100%
• Protein Binding 33%
• Cytochrome P450 33%
• Piperazine 33%
• Binding Assay 33%