TY - JOUR
T1 - New therapies for glaucoma
T2 - Are they all up to the task?
AU - Yorio, Thomas
AU - Dibas, Adnan
N1 - Funding Information:
The support of NIH NEI grant EY 11979 is recognised.
PY - 2004/12
Y1 - 2004/12
N2 - This review summarises the patenting activity in the anti-glaucoma field for the period 2001 - 2004. The various patents are classified based on the targeted mechanism of claimed drugs. New drugs, especially in the area of neuroprotection, are covered. Whereas some of the patent applications represent new areas in the treatment of glaucoma, others represent improved or modified classes of current anti-glaucoma drugs given to patients. However, most of the patent applications lack clinical data and some even lack data supporting their glaucoma efficacy claims. The authors have attempted to highlight, where possible, a number of promising drugs for the treatment of glaucoma. These are not all inclusive and represent the authors bias in selection. Some areas that were not included (e.g., calcium channel blockers, K+ channel agents, etc) are still equally important.
AB - This review summarises the patenting activity in the anti-glaucoma field for the period 2001 - 2004. The various patents are classified based on the targeted mechanism of claimed drugs. New drugs, especially in the area of neuroprotection, are covered. Whereas some of the patent applications represent new areas in the treatment of glaucoma, others represent improved or modified classes of current anti-glaucoma drugs given to patients. However, most of the patent applications lack clinical data and some even lack data supporting their glaucoma efficacy claims. The authors have attempted to highlight, where possible, a number of promising drugs for the treatment of glaucoma. These are not all inclusive and represent the authors bias in selection. Some areas that were not included (e.g., calcium channel blockers, K+ channel agents, etc) are still equally important.
KW - Glaucoma
KW - Intraocular pressure
KW - Neuroprotection
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=10344222102&partnerID=8YFLogxK
U2 - 10.1517/13543776.14.12.1743
DO - 10.1517/13543776.14.12.1743
M3 - Review article
AN - SCOPUS:10344222102
SN - 1354-3776
VL - 14
SP - 1743
EP - 1762
JO - Expert Opinion on Therapeutic Patents
JF - Expert Opinion on Therapeutic Patents
IS - 12
ER -