New Jersey Caucasian, African American, and Hispanic population data on the PCR-based loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc

Linda B. Jankowski, Bruce Budowle, Nancy T. Swec, Joseph A. Pino, Sharon Freck-Tootell, Harry W. Corey, Robyn Schwartz, Edward J. LaRue, William L. Rochin, Charles J. Kearney, Margaret L. Tarver

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

New Jersey Caucasian, African American, and Hispanic genotype and allele frequencies were determined for the six PCR-based loci, HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc. All but one locus (HLA-DQA1 for African Americans) meet Hardy-Weinberg expectations. However, observing one departure in 18 loci over the three New Jersey sample populations is not unexpected. There is little evidence for departures from independence between pairs of loci in the three populations studied. Thus, multiple locus profile frequencies can be determined using the product rule.

Original languageEnglish
Pages (from-to)1037-1040
Number of pages4
JournalJournal of Forensic Sciences
Volume43
Issue number5
DOIs
StatePublished - Sep 1998

Keywords

  • D7S8
  • DNA typing
  • Forensic science
  • GYPA
  • Gc
  • HBGG
  • HLA DQA1
  • Hardy-Weinberg equilibrium
  • LDLR
  • Linkage equilibrium
  • PCR
  • Population genetics

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    Jankowski, L. B., Budowle, B., Swec, N. T., Pino, J. A., Freck-Tootell, S., Corey, H. W., Schwartz, R., LaRue, E. J., Rochin, W. L., Kearney, C. J., & Tarver, M. L. (1998). New Jersey Caucasian, African American, and Hispanic population data on the PCR-based loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc. Journal of Forensic Sciences, 43(5), 1037-1040. https://doi.org/10.1520/jfs14353j