Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents

Keyphrases

• Neuroprotective Effect 100%
• Rodents 100%
• ASIC1a 100%
• Inhibiting Effect 100%
• Optic Nerve Crush Model 100%
• Optic Nerve Crush 90%
• Calpain 40%
• Psalmotoxin 40%
• Retinal Ganglion Cell Survival 30%
• Amiloride 30%
• Glial Fibrillary Acidic Protein 20%
• One-way Analysis of Variance 20%
• Aminoethyl 20%
• Glutamine Synthetase 20%
• Fodrin 20%
• Intraocular Pressure 10%
• Neuronal Death 10%
• Central Nervous System 10%
• Protein Level 10%
• Ca2+ 10%
• Endoplasmic Reticulum 10%
• Retinal Ganglion Cell Death 10%
• Retina 10%
• Optic Nerve 10%
• Retinal Ganglion Cells 10%
• Brain-derived Neurotrophic Factor 10%
• Insults 10%
• Plasma Membrane 10%
• Morphological Changes 10%
• Extracellular Calcium 10%
• Polymerase Chain Reaction 10%
• Beta-blockers 10%
• Optic Nerve Degeneration 10%
• Potential Therapeutics 10%
• Room Temperature 10%
• Induced Degradation 10%
• Ethylene Glycol 10%
• Bicinchoninic Acid 10%
• Hydrochloride 10%
• Benzenesulfonyl Fluoride 10%
• Ringer 10%
• Intracellular Ca2+ 10%
• Ethylenediaminetetraacetic Acid 10%
• Standard Error of the Mean 10%
• Ciliary Neurotrophic Factor 10%
• Dimethyl Sulfoxide 10%
• Phosphate-buffered Saline 10%
• RNA Binding Protein with multiple Splicing 10%
• Acidification 10%
• Ether 10%

Neuroscience

• Neuroprotective Agent 100%
• Optic Nerve 100%
• Acid-Sensing Ion Channel 100%
• Retinal Ganglion Cell 41%
• Calpain 1 25%
• Cell Survival 25%
• Amiloride 25%
• Glial Fibrillary Acidic Protein 16%
• Glutamate Ammonia Ligase 16%
• Fodrin 16%
• Intraocular Pressure 8%
• Central Nervous System 8%
• Neuronal Cell Death 8%
• Cell Death 8%
• Brain-Derived Neurotrophic Factor 8%
• Cell Membrane 8%
• Neurodegeneration 8%
• Calpain 8%
• Ethylenediaminetetraacetic Acid 8%
• Endoplasmic reticulum 8%
• Dimethyl Sulfoxide 8%
• Chloride 8%
• Ethylene Glycol 8%
• Phosphate Buffered Saline 8%
• Ciliary Neurotrophic Factor 8%
• RNA-binding Protein 8%
• Polymerase Chain Reaction 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Neuroprotective Agent 100%
• Nerve Crush 100%
• Acid Sensing Ion Channel 100%
• Calpain 1 30%
• Amiloride 30%
• Calcium Ion 20%
• Glial Fibrillary Acidic Protein 20%
• Fodrin 20%
• Glutamate Ammonia Ligase 20%
• Injury 10%
• Nerve Degeneration 10%
• Buffer 10%
• Ethylenediaminetetraacetic Acid 10%
• Ciliary Neurotrophic Factor 10%
• Dimethyl Sulfoxide 10%
• Egtazic Acid 10%
• Calpain 10%
• Brain Derived Neurotrophic Factor 10%
• Chloride 10%
• Phosphate Buffered Saline 10%
• Ethylene Glycol 10%
• 4 (2 Aminoethyl)benzenesulfonyl Fluoride 10%
• RNA Binding Protein 10%