Abstract
Background and Purpose:We investigated whether neuroglobin, a neuronal protein that protects neurons from hypoxic-ischemic injury, is upregulated in ischemic stroke. Methods: Neuroglobin immunoreactivity was measured in brain tissue from control subjects and patients with ischemic stroke. Results-Neuroglobin was detected in several brain areas, and its expression was increased in the cortical peri-infarct region after stroke. Conclusions:s: Ischemic stroke increases expression of the neuroprotective protein neuroglobin, suggesting neuroglobin may represent a novel target for stroke therapy.
Original language | English |
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Pages (from-to) | 557-559 |
Number of pages | 3 |
Journal | Stroke |
Volume | 41 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2010 |
Keywords
- Ischemia
- Neuroglobin
- Neuroprotection