Nanobiosensors: Role in cancer detection and diagnosis

Andrew Gdowski, Amalendu Prakash Ranjan, Anindita Mukerjee, Jamboor K. Vishwanatha

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The ability to detect many cancers at an early stage in its clinical course has the potential to improve patient outcomes in terms of morbidity and mortality. Nanosized components incorporated into existing clinical diagnostic and detection systems as well as novel nanobiosensors have demonstrated improved sensitivity and specificity compared with traditional cancer testing approaches. Nanoparticles, nanowires, nanotubes, and nanocantilevers are examples of four nanobiosensor systems that have been used experimentally in the context of detection and diagnosis of prostate, breast, pancreatic, lung, and brain cancers over the past few years. Nanobiosensors will begin to transition into clinically validated tests as experimental and engineering techniques advance. This paper presents examples of some such nanobiosensors for cancer diagnosis and detection.

Original languageEnglish
Pages (from-to)33-58
Number of pages26
JournalAdvances in Experimental Medicine and Biology
Volume807
DOIs
StatePublished - 1 Jan 2014

Keywords

  • Cancer detection and diagnosis
  • Nanobiosensors

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