TY - JOUR
T1 - Nanobiosensors
T2 - Role in cancer detection and diagnosis
AU - Gdowski, Andrew
AU - Ranjan, Amalendu P.
AU - Mukerjee, Anindita
AU - Vishwanatha, Jamboor K.
N1 - Publisher Copyright:
© Springer India 2014.
PY - 2014
Y1 - 2014
N2 - The ability to detect many cancers at an early stage in its clinical course has the potential to improve patient outcomes in terms of morbidity and mortality. Nanosized components incorporated into existing clinical diagnostic and detection systems as well as novel nanobiosensors have demonstrated improved sensitivity and specificity compared with traditional cancer testing approaches. Nanoparticles, nanowires, nanotubes, and nanocantilevers are examples of four nanobiosensor systems that have been used experimentally in the context of detection and diagnosis of prostate, breast, pancreatic, lung, and brain cancers over the past few years. Nanobiosensors will begin to transition into clinically validated tests as experimental and engineering techniques advance. This paper presents examples of some such nanobiosensors for cancer diagnosis and detection.
AB - The ability to detect many cancers at an early stage in its clinical course has the potential to improve patient outcomes in terms of morbidity and mortality. Nanosized components incorporated into existing clinical diagnostic and detection systems as well as novel nanobiosensors have demonstrated improved sensitivity and specificity compared with traditional cancer testing approaches. Nanoparticles, nanowires, nanotubes, and nanocantilevers are examples of four nanobiosensor systems that have been used experimentally in the context of detection and diagnosis of prostate, breast, pancreatic, lung, and brain cancers over the past few years. Nanobiosensors will begin to transition into clinically validated tests as experimental and engineering techniques advance. This paper presents examples of some such nanobiosensors for cancer diagnosis and detection.
KW - Cancer detection and diagnosis
KW - Nanobiosensors
UR - http://www.scopus.com/inward/record.url?scp=84903770675&partnerID=8YFLogxK
U2 - 10.1007/978-81-322-1777-0_4
DO - 10.1007/978-81-322-1777-0_4
M3 - Article
C2 - 24619617
AN - SCOPUS:84903770675
SN - 0065-2598
VL - 807
SP - 33
EP - 58
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
ER -