Muscle-type aldolase isolated from a liver tumor

L. W. Brox, A. G. Lacko, R. W. Gracy, R. C. Adelman, B. L. Horecker

Research output: Contribution to journalArticlepeer-review


Fructose diphosphate aldolase has been crystallized from a Novikoff ascites hepatoma and its properties compared with those of aldolases of normal rat liver and muscle. The identity of the tumor enzyme with the normal muscle enzyme was established on the basis of amino acid composition and tryptic fingerprints, as well as the sensitivity to inactivation by L-glyceraldehyde 3-phosphate.

Original languageEnglish
Pages (from-to)994-998
Number of pages5
JournalBiochemical and Biophysical Research Communications
Issue number6
StatePublished - 10 Sep 1969


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