Multi-Photon Sensitized Excitation of Near Infrared Emitting Lanthanides

Grzegorz Piszczek, Ignacy Gryczynski, Badri P. Maliwal, Joseph R. Lakowicz

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Near infrared (NIR) multi-photon excitation of the NIR-emitting lanthanides neodymium (Nd 3+) and ytterbium (Yb 3+) sensitized by a fluorescein-linked chelator was demonstrated. Because tissues display minimal absorbance near the excitation wavelength of 800 nm, and because the lanthanides display long decay times, these results suggest the use of Nd 3+ and Yb 3+ as luminescent probes in tissues with multi-photon excitation.

Original languageEnglish
Pages (from-to)15-17
Number of pages3
JournalJournal of Fluorescence
Issue number1
StatePublished - Mar 2002


  • Fluorescence
  • Lanthanides
  • Multi-photon
  • Near infrared


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