Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage

Biochemistry, Genetics and Molecular Biology

• Homeostasis 100%
• HSF1 100%
• Heat Shock Transcription Factor 1 100%
• Factor I Deficiency 100%
• Adenine 40%
• Mitochondrial Permeability Transition Pore 40%
• Translocase 40%
• Mitochondrial Membrane Transport Protein 40%
• Carrier Protein 40%
• Glutathione 40%
• Downregulation 20%
• Knockout Mouse 20%
• Heat Shock Protein 20%
• Mitochondrial Protein 20%
• Protein Content 20%
• Hsp70 20%
• Hsp90 20%
• Glucose-6-Phosphate Dehydrogenase 20%
• Enzymatic Activity 20%
• Crystallin 20%

Keyphrases

• Mitochondrial Oxidative Stress 100%
• Heat Shock Factor 1 (HSF1) 100%
• Redox Homeostasis 100%
• Oxidative Damage 28%
• Glutathione 28%
• Hsp25 28%
• Adenine nucleotide Translocase 28%
• Antioxidant System 14%
• Glucose-6-phosphate Dehydrogenase (G6PD) 14%
• Knock-in Mouse Model 14%
• Chaperone 14%
• Heat Shock Proteins 14%
• Decreased Activity 14%
• Mitochondrial Proteins 14%
• Constitutive Expression 14%
• Protein Content 14%
• Mitochondrial Permeability Transition Pore Opening 14%
• Heat Shock Protein 90 (Hsp90) 14%
• αB-crystallin 14%
• Heat Shock Protein 70 (HSP70) 14%
• Redox State 14%
• Superoxide 14%
• Catalytic Activity 14%
• Heat Shock Protein 60 (HSP60) 14%
• Mitochondrial Permeability Transition Pore 14%
• Normal Heart 14%
• Disulfates 14%