Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity

Keyphrases

• Molecular Mechanism 100%
• Cannabinoids 100%
• N-methyl-D-aspartate 100%
• Neuronal Excitotoxicity 100%
• CB1 Receptor 87%
• Protective Effect 37%
• Receptor Knockout 37%
• Methyl 37%
• Wild Mice 25%
• 7-nitroindazole 25%
• SR141716A 25%
• NO Production 25%
• Protein Kinase 12%
• Neuronal Death 12%
• Knock-in Mouse Model 12%
• Diacetate 12%
• Cerebral Cortex 12%
• Aminoethyl 12%
• Hydrochloride 12%
• Methanone 12%
• Cortical Culture 12%
• Chlorophenyl 12%
• G Protein 12%
• Amino 12%
• Cultured Cortical Neurons 12%
• Pyrrol 12%
• Cannabinoid Agonists 12%
• 1H-pyrazole 12%
• Morpholinyl 12%
• Mesylate 12%
• Pyrazole-3-carboxamides 12%
• Piperidin 12%
• Cannabinoid Receptor Antagonists 12%
• Benzoxazinoids 12%
• Cortical Neuron Culture 12%
• Dibutyryl-cAMP 12%
• Lesion Size 12%
• Excitotoxic Damage 12%
• L-NAME 12%
• Nitric Oxide Synthase Inhibitors 12%
• Pertussis Toxin 12%
• Quinolinesulfonamides 12%
• Mouse Cerebral Cortex 12%
• NO Generation 12%
• Cerebrocortical Neurons 12%
• Neuronal Nitric Oxide Synthase (nNOS) 12%
• Protein Kinase A Signaling 12%
• Nitric Oxide Synthase Activity 12%

Neuroscience

• Excitotoxicity 100%
• Aspartic Acid 100%
• Cannabinoid 100%
• Cannabinoid 1 Receptor 87%
• In Vitro 25%
• Protein Kinase A 25%
• Nitric Oxide Synthase 25%
• Cerebral Cortex 25%
• Rimonabant 25%
• 7-Nitroindazole 25%
• Cyclic Adenosine Monophosphate 12%
• In Vivo 12%
• Neuronal Cell Death 12%
• Agonist 12%
• G Protein 12%
• Cannabinoid Receptor Antagonist 12%
• Carboxamide 12%
• Pyrazole 12%
• Arginine Methyl Ester 12%
• Pertussis Toxin 12%
• Sulfonamide 12%
• Isoquinoline 12%
• Neuronal Nitric Oxide Synthase 12%
• H-89 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Cyclic AMP Dependent Protein Kinase Inhibitor 12%
• Isoquinoline 12%