Mitigating prolonged QT interval in cancer nanodrug development for accelerated clinical translation

Keyphrases

• In Cancer 100%
• Curcumin 100%
• Clinical Translation 100%
• QT Prolongation 100%
• Nanodrug 100%
• Nanocurcumin 28%
• HERG Channel 28%
• Potent Drugs 28%
• Protective Behavior 14%
• Inhibition Rate 14%
• Clinical Application 14%
• HEK293 Cells 14%
• Clinical Evaluation 14%
• Drug Development 14%
• Lipids 14%
• Liposomal Curcumin 14%
• Nanoparticle Formulation 14%
• Hybrid Nanoparticles 14%
• Active Substances 14%
• Enhanced Stability 14%
• Channel Inhibition 14%
• Drug Discontinuation 14%
• High Failure Rate 14%
• Antitumor Properties 14%
• Pharmacologically Active 14%
• Low Bioavailability 14%
• Equivalent Concentration 14%
• Safe Drugs 14%
• Patch Clamp Assay 14%
• Post-marketing Surveillance 14%
• Pharmaceutical Agents 14%
• Cardiac Toxicity 14%
• Enhanced Bioavailability 14%
• Therapeutic Concentrations 14%
• HERG K+ Channel 14%
• Manual Patch Clamp 14%
• Drug Choice 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Curcumin 100%
• QT Prolongation 100%
• Bioavailability 25%
• Neoplasm 12%
• Nanoparticle 12%
• Clinical Trial 12%
• Drug Development 12%
• Potassium Channel 12%
• Cardiotoxicity 12%