Microcolumn size-exclusion chromatography coupled with electrospray ionization mass spectrometry

Laszlo Prokai, David J. Aaserud, William J. Simonsick

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Microcolumn (250x0.5 mm I.D.) size-exclusion chromatography was implemented for the separation of polydisperse mixtures prior to electrospray ionization (ESI) mass spectrometric detection. An improved separation, compared to conventional-bore SEC, was demonstrated upon coupling with ESI quadrupole ion-trap mass spectrometry and a Fourier transform ion cyclotron resonance instrument for the separation of individual oligomers present in octylphenoxypoly(ethoxy)ethanol. Copyright (C) 1999 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)121-126
Number of pages6
JournalJournal of Chromatography A
Issue number1-2
StatePublished - 12 Mar 1999


  • Liquid chromatography-mass spectrometry
  • Octylphenoxypoly(ethoxy)ethanol
  • Polymers
  • Size-exclusion chromatography


Dive into the research topics of 'Microcolumn size-exclusion chromatography coupled with electrospray ionization mass spectrometry'. Together they form a unique fingerprint.

Cite this