TY - JOUR
T1 - Microbiologic and clinical study of acute diarrhea in children in Aswan, Egypt
AU - Mikhail, Isis A.
AU - Hyams, Kenneth C.
AU - Podgore, John K.
AU - Haberberger, Richard L.
AU - Boghdadi, Abdulla M.
AU - Mansour, Noshy S.
AU - Woody, James N.
N1 - Funding Information:
This research was supported by the Naval Medical Research and Development Command, NMC, NCR, Bethesda, MD, USA, Work unit No. 3Ml61102BSlO.AA.421-3. The opinions and assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the views of the US Department of the Navy, the naval service at large, or the Ministry of Health of Egypt. Informed consent was obtained from patients or their immediate relatives and guidelines for human experimentation of the NAMRU-3 Committee for the Protection of Human Subjects were followed in the conduct of this research.
PY - 1989
Y1 - 1989
N2 - Children with diarrhea presenting to a Government Rehydration Center in Aswan, Egypt, were investigated to determine the etiology and clinical presentation of acute childhood diarrhea in southern Egypt. Among 126 outpatients and 25 inpatients with diarrhea (mean age 18 months), enterotoxigenic Escherichia coli (EXEC) (17% of cases), Cryptosporidium (9% Salmonella spp. (7% Campylobacter jejuni/coli (7% and Shigella spp. (5% were the most common enteropathogens identified during the high incidence season of July. Enteropathogens were isolated as often from inpatients as outpatients, except for Salmonella spp. and Cryptosporidium, which were recovered more often from inpatients. Salmonella-infected children, in particular, were more ill, feverish, and dehydrated on presentation than other children, resulting in more frequent hospitalization. Except for Salmonella-infected children, children with acute diarrhea usually presented without severe dehydration, which may have been due to frequent initiation of oral rehydration therapy (ORT) by mothers trained by local health care providers. A potential environmental source of ETEC was identified in clay water storage containers commonly used in this area.
AB - Children with diarrhea presenting to a Government Rehydration Center in Aswan, Egypt, were investigated to determine the etiology and clinical presentation of acute childhood diarrhea in southern Egypt. Among 126 outpatients and 25 inpatients with diarrhea (mean age 18 months), enterotoxigenic Escherichia coli (EXEC) (17% of cases), Cryptosporidium (9% Salmonella spp. (7% Campylobacter jejuni/coli (7% and Shigella spp. (5% were the most common enteropathogens identified during the high incidence season of July. Enteropathogens were isolated as often from inpatients as outpatients, except for Salmonella spp. and Cryptosporidium, which were recovered more often from inpatients. Salmonella-infected children, in particular, were more ill, feverish, and dehydrated on presentation than other children, resulting in more frequent hospitalization. Except for Salmonella-infected children, children with acute diarrhea usually presented without severe dehydration, which may have been due to frequent initiation of oral rehydration therapy (ORT) by mothers trained by local health care providers. A potential environmental source of ETEC was identified in clay water storage containers commonly used in this area.
UR - http://www.scopus.com/inward/record.url?scp=0024537083&partnerID=8YFLogxK
U2 - 10.3109/00365548909035681
DO - 10.3109/00365548909035681
M3 - Article
C2 - 2658018
AN - SCOPUS:0024537083
SN - 0036-5548
VL - 21
SP - 59
EP - 65
JO - Scandinavian Journal of Infectious Diseases
JF - Scandinavian Journal of Infectious Diseases
IS - 1
ER -