TY - JOUR
T1 - Metal-enhanced fluorescence
T2 - Potential applications in HTS
AU - Geddes, Chris D.
AU - Gryczynski, Ignacy
AU - Malicka, Joanna
AU - Gryczynski, Zygmunt
AU - Lakowicz, Joseph R.
PY - 2003/3
Y1 - 2003/3
N2 - Metallic surfaces and particles can have dramatic effects on fluorescence, including localized excitation, increased quantum yields, increased photostability and increased distances for resonance energy transfer (RET), and directional emission. While all these effects have not yet been realized in a single system, metal-enhanced fluorescence promises to provide the next generation of high sensitivity fluorescence assays for low copy number detection of biochemical species.
AB - Metallic surfaces and particles can have dramatic effects on fluorescence, including localized excitation, increased quantum yields, increased photostability and increased distances for resonance energy transfer (RET), and directional emission. While all these effects have not yet been realized in a single system, metal-enhanced fluorescence promises to provide the next generation of high sensitivity fluorescence assays for low copy number detection of biochemical species.
UR - http://www.scopus.com/inward/record.url?scp=0345505306&partnerID=8YFLogxK
U2 - 10.2174/1386207033329760
DO - 10.2174/1386207033329760
M3 - Review article
C2 - 12678706
AN - SCOPUS:0345505306
SN - 1386-2073
VL - 6
SP - 109
EP - 117
JO - Combinatorial Chemistry and High Throughput Screening
JF - Combinatorial Chemistry and High Throughput Screening
IS - 2
ER -