Abstract
Indocyanine green (ICC) is widely used in medical imaging and testing. Its complex spectral behavior and low quantum yield limits some applications. We show that proximity of ICG to a metallic silver particle increases its intensity approximately 20-fold and decreases the decay time. Since the rate of photobleaching is not increased, our results suggest that ICG-silver particle complexes can yield at least 20-fold more photons per ICG molecule for improved medical imaging.
Original language | English |
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Pages (from-to) | 472-478 |
Number of pages | 7 |
Journal | Journal of Biomedical Optics |
Volume | 8 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2003 |
Keywords
- Idocyanine green
- Metal-enhanced fluorescence
- Silver islands