Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2-4Bl in MCF-7 breast cancer cells

Keyphrases

• Breast Cancer Cells 100%
• Cytotoxic Activity 100%
• MCF-7 100%
• Control Cell 100%
• Mechanistic Studies 100%
• Mesoionic Compounds 100%
• Autophagy 66%
• Microarray Analysis 66%
• Cytotoxic Effect 66%
• Light Chain 3 66%
• Protein Expression 33%
• Mitochondrial Membrane Potential 33%
• Growth Factors 33%
• Quantitative PCR 33%
• Western Blot Analysis 33%
• PCR Analysis 33%
• Breast Cancer 33%
• Protein Markers 33%
• Adhesion Molecules 33%
• Change of Measure 33%
• Changes in Gene Expression 33%
• Protein Expression Level 33%
• Oxygen Consumption Rate 33%
• IC50 Value 33%
• Associated Proteins 33%
• Microtubules 33%
• Respiratory Parameters 33%
• Activating Transcription Factor 3 (ATF3) 33%
• Heparin 33%
• Breast Cancer Cell Lines 33%
• Expression Change 33%
• RGS2 33%
• Six Genes 33%
• ATG5 33%
• Mitochondrial Respiration 33%
• Thiolate 33%
• Change Analysis 33%
• Response Curve 33%
• In Vivo Investigation 33%
• Rate Analysis 33%
• Crystal Violet Assay 33%
• Dickkopf WNT Signaling Pathway Inhibitor 1 33%
• Ig-like Domain 33%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Cytotoxicity 100%
• Autophagy 66%
• Microarrays 66%
• Light Chain 66%
• Signal Transduction 33%
• Western Blot 33%
• Gene Expression 33%
• Real-Time Polymerase Chain Reaction 33%
• RNA 33%
• Cell Adhesion Molecule 33%
• Quantitative Reverse Transcription Polymerase Chain Reaction 33%
• Protein Expression Level 33%
• Mitochondrial Membrane Potential 33%
• Growth Factor 33%
• IC50 33%
• Oxygen Consumption 33%
• Heparin 33%
• Regulator of G Protein Signalling 33%
• Mitochondrial Respiration 33%
• Immunoglobulin Domain 33%
• Activating Transcription Factor 3 33%
• ATG5 33%
• Thiolates 33%