Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging

Keyphrases

• Fluorescence Anisotropy 100%
• Drug Target Engagement 100%
• Fluorescence Anisotropy Imaging 100%
• Living Cells 100%
• Two-photon Fluorescence 100%
• Fluorophore 50%
• Whole Organism 50%
• Fluorescence Lifetime 50%
• Target Engagement 50%
• Drug Target 50%
• Microscopy 50%
• Molecular Pharmacology 50%
• Drug Distribution 50%
• Drug Development 50%
• Fluorescently Labeled 50%
• Targeted Drugs 50%
• Spectroscopic Techniques 50%
• Accurate Model 50%
• Sample Preparation 50%
• Polarized Light 50%
• Daylight Analysis 50%
• Binding Interaction 50%
• Quantitative Parameters 50%
• Drug Action 50%
• Protocol Optimization 50%
• Drug Binding 50%
• Olympus 50%
• Target Characterization 50%
• Direct Characterization 50%
• Interactions between Molecules 50%
• Stream Processing 50%
• Rotational Correlation 50%
• Target Measurement 50%
• Subcellular Resolution 50%
• Dual-channel 50%

Biochemistry, Genetics and Molecular Biology

• Fluorescence Anisotropy 100%
• Lifespan 33%
• Dynamics 33%
• Spectroscopy 33%
• Drug Mechanism 33%
• Drug Binding 33%
• Drug Distribution 33%

Chemistry

• Drug Target 100%
• Anisotropy 100%
• Fluorescence Lifetime 33%
• Spectroscopy 33%