Mass spectrometry-based retina proteomics

Research output: Contribution to journalReview articlepeer-review

Abstract

A subfield of neuroproteomics, retina proteomics has experienced a transformative growth since its inception due to methodological advances in enabling chemical, biochemical, and molecular biology techniques. This review focuses on mass spectrometry's contributions to facilitate mammalian and avian retina proteomics to catalog and quantify retinal protein expressions, determine their posttranslational modifications, as well as its applications to study the proteome of the retina in the context of biology, health and diseases, and therapy developments.

Original languageEnglish
JournalMass Spectrometry Reviews
DOIs
StateAccepted/In press - 2022

Keywords

  • biomarkers
  • estrogenic retina
  • photobiology
  • posttranslational modifications
  • protein expression
  • proteomics
  • retina
  • retinal diseases
  • therapeutic targets

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