Long-lifetime lipid rhenium metal-ligand complex for probing membrane dynamics on the microsecond timescale

Li Li; Felix N. Castellano; Ignacy Gryczynski; Joseph R. Lakowicz

doi:10.1016/S0009-3084(99)00002-X

Long-lifetime lipid rhenium metal-ligand complex for probing membrane dynamics on the microsecond timescale

Li Li, Felix N. Castellano, Ignacy Gryczynski, Joseph R. Lakowicz

Microbiology, Immunology & Genetics

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We report the luminescence and spectral properties of a phospholipid analogue containing a long-lifetime luminescent rhenium metal-ligand complex (MLC) covalently linked to the amino group of phosphatidyl ethanolamine. When incorporated into synthetic membranes, this lipid probe displays intensity decay times near 3 μs. Importantly, the probe displays highly polarized emission with a maximal fundamental anisotropy of 0.33. This probe is expected to have numerous applications for studies of microsecond diffusion and dynamics of membranes. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	1-9
Number of pages	9
Journal	Chemistry and Physics of Lipids
Volume	99
Issue number	1
DOIs	https://doi.org/10.1016/S0009-3084(99)00002-X
State	Published - May 1999

Keywords

Long-lifetime lipid
Membrane dynamics
Rhenium metal-ligand complex

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10.1016/S0009-3084(99)00002-X

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abstract = "We report the luminescence and spectral properties of a phospholipid analogue containing a long-lifetime luminescent rhenium metal-ligand complex (MLC) covalently linked to the amino group of phosphatidyl ethanolamine. When incorporated into synthetic membranes, this lipid probe displays intensity decay times near 3 μs. Importantly, the probe displays highly polarized emission with a maximal fundamental anisotropy of 0.33. This probe is expected to have numerous applications for studies of microsecond diffusion and dynamics of membranes. Copyright (C) 1999 Elsevier Science Ireland Ltd.",

keywords = "Long-lifetime lipid, Membrane dynamics, Rhenium metal-ligand complex",

author = "Li Li and Castellano, {Felix N.} and Ignacy Gryczynski and Lakowicz, {Joseph R.}",

note = "Funding Information: The authors acknowledge the National Institutes of Health (GM-35154 and RR-08119) for the support of this research. FNC was supported by a NIH fellowship. ",

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AU - Li, Li

AU - Castellano, Felix N.

AU - Gryczynski, Ignacy

AU - Lakowicz, Joseph R.

N1 - Funding Information: The authors acknowledge the National Institutes of Health (GM-35154 and RR-08119) for the support of this research. FNC was supported by a NIH fellowship.

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N2 - We report the luminescence and spectral properties of a phospholipid analogue containing a long-lifetime luminescent rhenium metal-ligand complex (MLC) covalently linked to the amino group of phosphatidyl ethanolamine. When incorporated into synthetic membranes, this lipid probe displays intensity decay times near 3 μs. Importantly, the probe displays highly polarized emission with a maximal fundamental anisotropy of 0.33. This probe is expected to have numerous applications for studies of microsecond diffusion and dynamics of membranes. Copyright (C) 1999 Elsevier Science Ireland Ltd.

AB - We report the luminescence and spectral properties of a phospholipid analogue containing a long-lifetime luminescent rhenium metal-ligand complex (MLC) covalently linked to the amino group of phosphatidyl ethanolamine. When incorporated into synthetic membranes, this lipid probe displays intensity decay times near 3 μs. Importantly, the probe displays highly polarized emission with a maximal fundamental anisotropy of 0.33. This probe is expected to have numerous applications for studies of microsecond diffusion and dynamics of membranes. Copyright (C) 1999 Elsevier Science Ireland Ltd.

KW - Long-lifetime lipid

KW - Membrane dynamics

KW - Rhenium metal-ligand complex

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ER -

Long-lifetime lipid rhenium metal-ligand complex for probing membrane dynamics on the microsecond timescale

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Keywords

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