@inbook{d2b2424ccfd64720a65f494381eabb1e,
title = "Lipoproteins and the Tumor Microenvironment",
abstract = "The tumor microenvironment (TME) plays a key role in enhancing the growth of malignant tumors and thus contributing to “aggressive phenotypes,” supporting sustained tumor growth and metastasis. The precise interplay between the numerous components of the TME that contribute to the emergence of these aggressive phenotypes is yet to be elucidated and currently under intense investigation. The purpose of this article is to identify specific role(s) for lipoproteins as part of these processes that facilitate (or oppose) malignant growth as they interact with specific components of the TME during tumor development and treatment. Because of the scarcity of literature reports regarding the interaction of lipoproteins with the components of the tumor microenvironment, we were compelled to explore topics that were only tangentially related to this topic, to ensure that we have not missed any important concepts.",
keywords = "Adipose cells, Endothelial cells, Exosomes, Fibroblasts, High-density lipoproteins, Immune surveillance, Lipoproteins, Macrophage polarization, Macrophages, Metastasis, Microvasculature, Neutrophils, Pericytes, Tumor aggressiveness, Tumor environment",
author = "Dossou, {Akpedje Serena} and Nirupama Sabnis and Bhavani Nagarajan and Ezek Mathew and Rafal Fudala and Lacko, {Andras G.}",
note = "Funding Information: The authors{\textquoteright} research is supported by the Rutledge Cancer Foundation, the Texas Alzheimer{\textquoteright}s Research and Care Consortium, the Virginia Kincaid Charitable Trust, and Wheels for Wellness, Fort Worth TX. Publisher Copyright: {\textcopyright} 2020, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.",
year = "2020",
doi = "10.1007/978-3-030-48457-6_6",
language = "English",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "93--116",
booktitle = "Advances in Experimental Medicine and Biology",
}