Abstract
Hair samples were typed from three individuals who exhibited length heteroplasmy in the homopolymeric cytosine stretches (C-stretch) in hypervariable region 2 (HV2). The study demonstrated that for different hairs within an individual, the HV2 C-stretch region can vary with respect to the number of cytosines and/or proportion of C-stretch length variants. Length heteroplasmy may occur regardless of the prominent length variant present in this region. Differences in the number of cytosines at the C-stretch region, or a variation in the relative amounts of heteroplasmic length variants, cannot be used to support an interpretation of exclusion.
Original language | English |
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Pages (from-to) | 862-870 |
Number of pages | 9 |
Journal | Journal of Forensic Sciences |
Volume | 46 |
Issue number | 4 |
DOIs | |
State | Published - 2001 |
Keywords
- C-stretch
- Forensic science
- Length heteroplasmy
- Mitochondrial DNA