KE108-conjugated unimolecular micelles loaded with a novel HDAC inhibitor thailandepsin-A for targeted neuroendocrine cancer therapy

Medicine & Life Sciences

• thailandepsin A 100%
• Tyr(0)-(cyclo-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) 97%
• Micelles 52%
• Histone Deacetylase Inhibitors 51%
• Neuroendocrine Cells 18%
• somatostatin receptor type 1 15%
• cyanine dye 5 15%
• Neoplasms 14%
• Somatostatin 10%
• PEG-PAMAM 10%
• Poly(amidoamine) 7%
• Therapeutics 7%
• Peptides 6%
• Ethylene Glycol 5%
• Octreotide 5%
• Neuroendocrine Tumors 5%
• Optical Imaging 5%
• Nude Mice 4%
• Coloring Agents 4%
• Ligands 3%
• Neoplasm Metastasis 3%
• Cell Line 2%
• Morbidity 2%
• Growth 2%
• In Vitro Techniques 2%
• Pharmaceutical Preparations 2%

Engineering & Materials Science

• Micelles 65%
• Peptides 14%
• Polyethylene glycols 14%
• Tumors 11%
• Cells 10%
• Fluorescence imaging 8%
• Cell growth 7%
• Block copolymers 7%
• Ligands 7%
• Toxicity 6%
• Assays 6%
• Dyes 6%
• Stars 5%
• Surgery 5%
• Infrared radiation 4%

Chemical Compounds

• Micelle 34%
• Cy5 Dye 9%
• Octreotide 8%
• Somatostatin 7%
• Peptide 6%
• Size Distribution 4%
• Ethylene Glycol 4%
• Block Copolymer 4%
• Fluorescence 3%
• Drug 2%
• Ligand 2%