Italian population data on two new short tandem repeat loci: D2S1338 and Penta E

Luciano Garofano; Marco Pizzamiglio; Francesco Donato; Fulvio Biondi; Matteo Rossetti; Bruce Budowle

doi:10.1016/S0379-0738(99)00132-2

Italian population data on two new short tandem repeat loci: D2S1338 and Penta E

Luciano Garofano, Marco Pizzamiglio, Francesco Donato, Fulvio Biondi, Matteo Rossetti, Bruce Budowle

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A population study on two new short tandem repeat (STR) loci D2S1338 (a tetranucleotide repeat) and Penta E (a pentanucleotide repeat) was performed on 208 unrelated Italian Caucasians. The DNA was amplified by polymerase chain reaction (PCR) and separation and detection of the amplified STR fragments were carried out by use of a PE/ABD PRISM 377 DNA Sequencer 377 automated system (Applied Biosystems Division/Perkin-Elmer). Both loci meet Hardy-Weinberg expectations. There is no evidence for departures from expectations between the two loci. The combined Probability of Discrimination and Probability of Exclusion for the two STR loci are 0.999155 and 0.944925, respectively. The results demonstrate that these two regions can be useful for differentiating among individuals, particularly in concert with other STR loci. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	131-136
Number of pages	6
Journal	Forensic Science International
Volume	105
Issue number	2
DOIs	https://doi.org/10.1016/S0379-0738(99)00132-2
State	Published - 1 Nov 1999

Keywords

DNA
Forensic science
Population studies
STR

Access to Document

10.1016/S0379-0738(99)00132-2

Cite this

@article{63d47015164e40abb23a9f01e66f84e2,

title = "Italian population data on two new short tandem repeat loci: D2S1338 and Penta E",

abstract = "A population study on two new short tandem repeat (STR) loci D2S1338 (a tetranucleotide repeat) and Penta E (a pentanucleotide repeat) was performed on 208 unrelated Italian Caucasians. The DNA was amplified by polymerase chain reaction (PCR) and separation and detection of the amplified STR fragments were carried out by use of a PE/ABD PRISM 377 DNA Sequencer 377 automated system (Applied Biosystems Division/Perkin-Elmer). Both loci meet Hardy-Weinberg expectations. There is no evidence for departures from expectations between the two loci. The combined Probability of Discrimination and Probability of Exclusion for the two STR loci are 0.999155 and 0.944925, respectively. The results demonstrate that these two regions can be useful for differentiating among individuals, particularly in concert with other STR loci. Copyright (C) 1999 Elsevier Science Ireland Ltd.",

keywords = "DNA, Forensic science, Population studies, STR",

author = "Luciano Garofano and Marco Pizzamiglio and Francesco Donato and Fulvio Biondi and Matteo Rossetti and Bruce Budowle",

year = "1999",

month = nov,

day = "1",

doi = "10.1016/S0379-0738(99)00132-2",

language = "English",

volume = "105",

pages = "131--136",

journal = "Forensic Science International",

issn = "0379-0738",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Italian population data on two new short tandem repeat loci

T2 - D2S1338 and Penta E

AU - Garofano, Luciano

AU - Pizzamiglio, Marco

AU - Donato, Francesco

AU - Biondi, Fulvio

AU - Rossetti, Matteo

AU - Budowle, Bruce

PY - 1999/11/1

Y1 - 1999/11/1

N2 - A population study on two new short tandem repeat (STR) loci D2S1338 (a tetranucleotide repeat) and Penta E (a pentanucleotide repeat) was performed on 208 unrelated Italian Caucasians. The DNA was amplified by polymerase chain reaction (PCR) and separation and detection of the amplified STR fragments were carried out by use of a PE/ABD PRISM 377 DNA Sequencer 377 automated system (Applied Biosystems Division/Perkin-Elmer). Both loci meet Hardy-Weinberg expectations. There is no evidence for departures from expectations between the two loci. The combined Probability of Discrimination and Probability of Exclusion for the two STR loci are 0.999155 and 0.944925, respectively. The results demonstrate that these two regions can be useful for differentiating among individuals, particularly in concert with other STR loci. Copyright (C) 1999 Elsevier Science Ireland Ltd.

AB - A population study on two new short tandem repeat (STR) loci D2S1338 (a tetranucleotide repeat) and Penta E (a pentanucleotide repeat) was performed on 208 unrelated Italian Caucasians. The DNA was amplified by polymerase chain reaction (PCR) and separation and detection of the amplified STR fragments were carried out by use of a PE/ABD PRISM 377 DNA Sequencer 377 automated system (Applied Biosystems Division/Perkin-Elmer). Both loci meet Hardy-Weinberg expectations. There is no evidence for departures from expectations between the two loci. The combined Probability of Discrimination and Probability of Exclusion for the two STR loci are 0.999155 and 0.944925, respectively. The results demonstrate that these two regions can be useful for differentiating among individuals, particularly in concert with other STR loci. Copyright (C) 1999 Elsevier Science Ireland Ltd.

KW - DNA

KW - Forensic science

KW - Population studies

KW - STR

UR - http://www.scopus.com/inward/record.url?scp=0032848215&partnerID=8YFLogxK

U2 - 10.1016/S0379-0738(99)00132-2

DO - 10.1016/S0379-0738(99)00132-2

M3 - Article

C2 - 10605082

AN - SCOPUS:0032848215

SN - 0379-0738

VL - 105

SP - 131

EP - 136

JO - Forensic Science International

JF - Forensic Science International

IS - 2

ER -

Italian population data on two new short tandem repeat loci: D2S1338 and Penta E

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this