Italian population data on the polymarker system and on the five short tandem repeat loci CSF1PO, TPOX, TH01, F13B, and vWA

Luciano Garofano, Gianpietro Lago, Cesare Vecchio, Marco Pizzamiglio, Carlo Zanon, Antonino Virgili, Loredana Albonici, Vittorio Manzari, Bruce Budowle

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Abstract

A population study on five short tandem repeat (STR) loci and five sequence specific polymorphism loci was performed on unrelated Italian Caucasians. Separation and detection of the amplified STR fragments were carried out by high resolution vertical denaturing polyacrylamide gel electrophoresis (PAGE) and silver staining, respectively. The sequence specific loci were analyzed using the AmpliType PM Typing Kit (Perkin Elmer, Foster City, CA). All loci, except Gc (p = 0.031), meet Hardy-Wienberg expectations. In addition, there is no evidence for association of alleles between pairs of loci. The combined power of discrimination for the five STR loci is 0.9999862 and for the PM loci is 0.99503. The results suggest that these loci may be useful for human identification cases in Italy.

Original languageEnglish
Pages (from-to)837-840
Number of pages4
JournalJournal of Forensic Sciences
Volume43
Issue number4
StatePublished - 1 Jul 1998

Keywords

  • D7S8
  • DNA typing
  • Forensic science
  • GYPA
  • Gc
  • HBGG
  • HumCSF1PO
  • HumF13B
  • HumTH01
  • HumTPOX
  • HumvWA31
  • Ital y
  • LDLR
  • Population genetics

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    Garofano, L., Lago, G., Vecchio, C., Pizzamiglio, M., Zanon, C., Virgili, A., Albonici, L., Manzari, V., & Budowle, B. (1998). Italian population data on the polymarker system and on the five short tandem repeat loci CSF1PO, TPOX, TH01, F13B, and vWA. Journal of Forensic Sciences, 43(4), 837-840.