Interstitial fluid (peripheral lymph) lipoproteins

Ladislav Dory, Charles H. Sloop, Paul S. Roheim

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This chapter discusses the studies of interstitial fluid lipoproteins and their metabolism may provide the important link between tissue culture studies and in vivo studies of plasma lipoprotein metabolism. Perinodal peripheral lymph is an accepted model of interstitial fluid. The chapter also presents techniques, which allow collection of perinodal peripheral lymph in quantities sufficient for analytical or metabolic studies of interstitial fluid. The dog as an experimental model offers advantages in ease of surgical procedures, quantities of fluid obtained, and a well-characterized plasma lipoprotein profile. The experimental designs and data presented are examples of the potentially important information that can be obtained from studies of peripheral (or deep muscle) lymph lipoproteins. The chapter provides a link between studies on plasma lipoprotein metabolism and tissue culture studies using peripheral cell cultures (such as macrophage, smooth muscle cells, or endothelial cells) and thus provide an important contribution to the understanding of the function of lipoproteins.

Original languageEnglish
Pages (from-to)660-678
Number of pages19
JournalMethods in Enzymology
Volume129
Issue numberC
DOIs
StatePublished - 1 Jan 1986

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Extracellular Fluid
Lymph
Lipoproteins
Fluids
Metabolism
Tissue culture
Plasmas
Muscle
Macrophages
Endothelial cells
Cell culture
Design of experiments
Smooth Muscle Myocytes
Research Design
Theoretical Models
Endothelial Cells
Cell Culture Techniques
Cells
Dogs
Muscles

Cite this

Dory, Ladislav ; Sloop, Charles H. ; Roheim, Paul S. / Interstitial fluid (peripheral lymph) lipoproteins. In: Methods in Enzymology. 1986 ; Vol. 129, No. C. pp. 660-678.
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Interstitial fluid (peripheral lymph) lipoproteins. / Dory, Ladislav; Sloop, Charles H.; Roheim, Paul S.

In: Methods in Enzymology, Vol. 129, No. C, 01.01.1986, p. 660-678.

Research output: Contribution to journalArticle

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