Interaction of bone marrow stem cells with other cells

Hongxia Zhang; Shengwei Huang; Jiangnan Hu; Brian Wang; Kunlin Jin

doi:10.1007/978-981-10-2929-5_4

Interaction of bone marrow stem cells with other cells

Hongxia Zhang, Shengwei Huang, Jiangnan Hu, Brian Wang, Kunlin Jin

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Transplantation of bone marrow stem cells (BMSCs) as a regenerative cell replacement therapy for stroke holds great promise. However, the mechanisms underlying functional recovery after stroke remain unclear. Clearly, BMSCs benefit the neurological dysfunction in either direct or indirect methods through the interaction with other cells. In this chapter, we review the direct and indirect interactions of transplanted BMSCs with HSCs, immune cells, neural stem cells (NSCs), neurons, astrocytes, and endothelial cells for better understanding of the mechanisms underlying BMSC-mediated neurological function improvement after stroke.

Original language	English
Title of host publication	Bone Marrow Stem Cell Therapy for Stroke
Publisher	Springer Singapore
Pages	81-105
Number of pages	25
ISBN (Electronic)	9789811029295
ISBN (Print)	9789811029288
DOIs	https://doi.org/10.1007/978-981-10-2929-5_4
State	Published - 1 Jan 2016

Keywords

Bone marrow stem cells
Immune cells
Interaction
Transplantation

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10.1007/978-981-10-2929-5_4

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AU - Huang, Shengwei

AU - Hu, Jiangnan

AU - Wang, Brian

AU - Jin, Kunlin

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AB - Transplantation of bone marrow stem cells (BMSCs) as a regenerative cell replacement therapy for stroke holds great promise. However, the mechanisms underlying functional recovery after stroke remain unclear. Clearly, BMSCs benefit the neurological dysfunction in either direct or indirect methods through the interaction with other cells. In this chapter, we review the direct and indirect interactions of transplanted BMSCs with HSCs, immune cells, neural stem cells (NSCs), neurons, astrocytes, and endothelial cells for better understanding of the mechanisms underlying BMSC-mediated neurological function improvement after stroke.

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KW - Immune cells

KW - Interaction

KW - Transplantation

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BT - Bone Marrow Stem Cell Therapy for Stroke

PB - Springer Singapore

ER -

Interaction of bone marrow stem cells with other cells

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Keywords

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