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Inhibition of p-mTOR represses transcription of PS1 and Notch 1-signaling
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Dive into the research topics of 'Inhibition of p-mTOR represses transcription of PS1 and Notch 1-signaling'. Together they form a unique fingerprint.
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Keyphrases
3xTg-AD
14%
4E-BP1
14%
Abeta
57%
Alzheimer's Disease Model
28%
Amyloid-β Protein Precursor (AβPP)
14%
Aβ Peptide
14%
Catalytic Subunit
14%
Cellular Homeostasis
14%
Cognitive Deficits
14%
Decreased Expression
14%
Hes1
28%
Mammalian Target of Rapamycin (mTOR)
100%
Mammalian Target of Rapamycin Signaling
42%
Notch Intracellular Domain
42%
Notch Receptors
14%
Notch Signaling
14%
Notch1
14%
Notch1 Signaling
100%
P70S6K
14%
Phosphorylation
100%
Presenilin
100%
Protein Level
28%
Rapamycin
71%
Tau Pathology
14%
γ-secretase
14%
Biochemistry, Genetics and Molecular Biology
Amyloid Precursor Protein
14%
Enzyme Active Site
14%
Gamma Secretase
14%
Homeostasis
14%
Mammalian Target of Rapamycin
100%
Mechanistic Target of Rapamycin
71%
Messenger RNA
14%
Mouse Model
14%
Notch
42%
Notch Signaling Pathway
14%
Notch-1
100%
Presenilin
100%
Tau
14%
Transcription
100%
Neuroscience
Alzheimer's Disease
28%
Amyloid Beta Protein
14%
Amyloid Precursor Protein
14%
Cognitive Disorders
14%
Enzyme Active Site
14%
Gamma Secretase
14%
Mammalian Target of Rapamycin
71%
Messenger RNA
14%
Notch
100%
Notch Signaling Pathway
14%
Notch1 Receptor
14%
Presenilin 1
100%
Sirolimus
71%