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Inhibition of p-mTOR represses PS1 transcription by reducing p-JNK
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Dive into the research topics of 'Inhibition of p-mTOR represses PS1 transcription by reducing p-JNK'. Together they form a unique fingerprint.
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Keyphrases
Mammalian Target of Rapamycin (mTOR)
100%
Phosphorylation
100%
Presenilin
100%
JNK1
100%
C-Jun N-terminal Kinase
66%
Rapamycin
55%
Specific Inhibitor
22%
SP600125
22%
Protein Level
11%
SK-N-SH Cells
11%
Kinase Inhibitor
11%
Inhibition Mechanism
11%
Stress Conditions
11%
Amyloid-β Protein Precursor (AβPP)
11%
Notch1 Signaling
11%
Notch Intracellular Domain
11%
Notch Receptors
11%
Basal Activity
11%
Catalytic Subunit
11%
Non-stress
11%
γ-secretase
11%
Aβ Peptide
11%
MTOR Protein
11%
Biochemistry, Genetics and Molecular Biology
Mammalian Target of Rapamycin
100%
Transcription
100%
Presenilin
100%
Kinase
66%
Phosphotransferase
66%
N-Terminus
66%
Notch-1
22%
P53
11%
Notch
11%
Enzyme Active Site
11%
Amyloid Precursor Protein
11%
Mechanistic Target of Rapamycin
11%
Gamma Secretase
11%
Neuroscience
Presenilin 1
100%
Kinase
66%
Amino Terminal Sequence
66%
Sirolimus
55%
Notch
22%
Amyloid Precursor Protein
11%
P53
11%
Mammalian Target of Rapamycin
11%
Cleft
11%
Notch1 Receptor
11%
Enzyme Active Site
11%
Amyloid Beta Protein
11%
Gamma Secretase
11%