Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

Keyphrases

• Acute Lymphoblastic Leukemia 100%
• Childhood Acute Lymphoblastic Leukemia 100%
• Relapse Risk 100%
• Ph-like 100%
• GATA3 100%
• Odds Ratio 16%
• Non-acute 16%
• SNP 8%
• Genotype 8%
• High Risk 8%
• Genetic Variation 8%
• Genomic Profiling 8%
• Genome-wide Association Study 8%
• Risk Allele 8%
• Poor Prognosis 8%
• Susceptibility Loci 8%
• CRLF2 8%
• Gene Signature 8%
• IKZF1 Deletion 8%
• Leukemia Relapse 8%
• GATA3 Expression 8%
• Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia 8%
• Treatment Risk 8%
• Gene mutation 8%
• Inherited Variants 8%
• GATA3 rs3824662 8%
• Early Treatment 8%
• Somatic Variants 8%

Biochemistry, Genetics and Molecular Biology

• GATA3 100%
• Single Nucleotide Polymorphism 25%
• Allele 25%
• Genotyping 25%
• Genetic Variation 25%
• Genome-Wide Association Study 25%
• Gene Mutation 25%
• IKZF1 25%
• CRLF2 25%
• Philadelphia Chromosome 25%

Immunology and Microbiology

• Transcription Factor GATA 3 100%
• Allele 25%
• Single Nucleotide Polymorphism 25%
• Genetic Variation 25%
• Gene Mutation 25%
• Philadelphia 1 Chromosome 25%
• Genome-Wide Association Study 25%