Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

Keyphrases

• Coding Variants 100%
• Acute Lymphoblastic Leukemia 100%
• Childhood Acute Lymphoblastic Leukemia 100%
• Cyclin-dependent Kinase Inhibitor 2A (CDKN2A) 100%
• Leukemia Risk 50%
• CDKN2B 50%
• Odds Ratio 25%
• Genetic Basis 25%
• Tumor Cells 25%
• Hypomorphic mutation 25%
• Genetic Variation 25%
• Genome-wide Association Study 25%
• Functional Studies 25%
• Hematopoietic Stem Cells 25%
• Genome-wide Significance 25%
• Protein-coding Genes 25%
• Tumor Suppressor 25%
• Leukemogenesis 25%
• Tumor Suppressor Activity 25%
• Missense Variants 25%
• Complex Role 25%
• P16INK4a 25%
• Germline Variants 25%

Biochemistry, Genetics and Molecular Biology

• Cyclin Dependent Kinase Inhibitor 2A 100%
• Tumor Suppressor Protein 50%
• CDKN2B 50%
• Germline 25%
• Germ Cell 25%
• Genetics 25%
• Genetic Divergence 25%
• Genetic Variation 25%
• Genome-Wide Association Study 25%
• Missense 25%
• P16 25%
• Hematopoietic Cell 25%