Inflammatory signaling in Alzheimer disease and depression

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21 Scopus citations


To help defi ne the relationships among infl ammation, Alzheimer disease, and depression, the Texas Alzheimer's Research Consortium analyzed an array of infl ammatory biomarkers in a cohort of patients with Alzheimer disease and in controls. Infl ammation severity was highly correlated with earlier age at onset of Alzheimer disease and was also associated with cognitive decline. The relationship between infl ammation and depression was not as clear, and it varied with aspects of depression, gender, and the presence of Alzheimer disease.

Original languageEnglish
Pages (from-to)S47-S49
JournalCleveland Clinic Journal of Medicine
Issue numberSUPPL. 1
StatePublished - 2011


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