Induced pluripotent stem cells: Generation, characterization, and differentiation—methods and protocols

Veronica Kon Graversen, Sai Chavala

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Reprogramming fibroblasts into induced pluripotent stem cells (iPSC) remains a promising technique for cell replacement therapy. Diverse populations of somatic cells have been examined for their reprogramming potential. Recently, ocular ciliary body epithelial cells (CECs) have been reprogrammed with high reprogramming efficiency and single transcription factor reprogramming, making them an exciting candidate for cellular reprogramming strategies.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages395-401
Number of pages7
DOIs
StatePublished - 1 Jan 2016

Publication series

NameMethods in Molecular Biology
Volume1357
ISSN (Print)1064-3745

Keywords

  • Ciliary body epithelial cells
  • Induced pluripotent stem cells
  • Reprogramming
  • Somatic cells
  • Transcription factors

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