@article{6fe70b27e8484dc192afa90aed2f5178,
title = "Increasing the reference populations for the 55 AISNP panel: the need and benefits",
abstract = "Ancestry inference for an individual can only be as good as the reference populations with allele frequency data on the SNPs being used. If the most relevant ancestral population(s) does not have data available for the SNPs studied, then analyses based on DNA evidence may indicate a quite distantly related population, albeit one among the more closely related of the existing reference populations. We have added reference population allele frequencies for 14 additional population samples (with >1100 individuals studied) to the 125 population samples previously published for the Kidd Lab 55 AISNP panel. Allele frequencies are now publicly available for all 55 SNPs in ALFRED and FROG-kb for a total of 139 population samples. This Kidd Lab panel of 55 ancestry informative SNPs has been incorporated in commercial kits by both ThermoFisher Scientific and Illumina for massively parallel sequencing. Researchers employing those kits will find the enhanced set of reference populations useful.",
keywords = "Alfred, Ancestry, FROG-kb, Reference database, SNP",
author = "Pakstis, {Andrew J.} and Longli Kang and Lijun Liu and Zhiying Zhang and Tianbo Jin and Grigorenko, {Elena L.} and Wendt, {Frank R.} and Bruce Budowle and Sibte Hadi and {Al Qahtani}, {Mariam Salam} and Niels Morling and Mogensen, {Helle Smidt} and Themudo, {Goncalo E.} and Usha Soundararajan and Haseena Rajeevan and Kidd, {Judith R.} and Kidd, {Kenneth K.}",
note = "Funding Information: The assembly and analyses of the data were funded primarily by NIJ Grants 2013-DN-BX-K023 and 2014–DN-BX-K030 to KKK awarded by the National Institute of Justice, Office of Justice Programs, U.S. Department of Justice, and Grant BCS-1444279 from the US National Science Foundation. Points of view in this presentation are those of the authors and do not necessarily represent the official position or policies of the U.S. Department of Justice. National Natural Science Foundation of China grants (31260252, 31760097, 31660307) to LK supported data collection. Acknowledgements for the collection of the individual sets of data are in the publications cited. Only the data for the eight new East Asian populations and the UAE Arabs are not fully published as yet and have been made available by the coauthors (LL, KK, ZZ, TJ, SH, MSQ) for this summary in advance of their full papers. Special thanks are due to the many hundreds of individuals who volunteered to give blood or saliva samples for studies of gene frequency variation and to the many colleagues who helped us collect the samples. Publisher Copyright: {\textcopyright} 2017, The Author(s).",
year = "2017",
month = jul,
day = "1",
doi = "10.1007/s00414-016-1524-z",
language = "English",
volume = "131",
pages = "913--917",
journal = "International Journal of Legal Medicine",
issn = "0937-9827",
publisher = "Springer Verlag",
number = "4",
}