Increased endoplasmic reticulum stress in human glaucomatous trabecular meshwork cells and tissues

Keyphrases

• Endoplasmic Reticulum Stress (ER stress) 100%
• Trabecular Meshwork 100%
• Glaucomatous 100%
• Trabecular Meshwork Cells 100%
• C/EBP Homologous Protein 50%
• Glucose-regulated Protein 78 (GRP78) 35%
• GRP94 35%
• Glaucoma 28%
• Stress Markers 28%
• Activating Transcription Factor 4 (ATF4) 28%
• Primary Open-angle Glaucoma 21%
• Age-matched 21%
• Western Blot Analysis 14%
• Tissue Lysate 14%
• Fold Increase 7%
• Elevated Intraocular Pressure 7%
• Ocular Hypertension 7%
• Protein Expression 7%
• Protein Level 7%
• Western Blot 7%
• Mouse Model 7%
• Immunohistochemistry 7%
• Outflow Resistance 7%
• Immunostaining 7%
• Human Donor 7%
• Pathogenic Mechanism 7%
• Immunohistochemical Analysis 7%
• Most Common Form 7%
• Aqueous Humor Outflow Resistance 7%
• Unfolded Protein Response 7%
• Glaucoma Treatment 7%
• Endoplasmic Reticulum Stress Pathway 7%
• Translation Initiation Factor eIF2 7%
• Disease-modifying Therapy 7%
• Densitometric Analysis 7%
• Eukaryotic Translation Initiation Factor 7%
• X-box Binding Protein 1 (XBP1) 7%

Neuroscience

• Trabecular Meshwork 100%
• Endoplasmic Reticulum Stress 100%
• Glaucoma 25%
• Glucose Regulated Protein 94 25%
• Activating Transcription Factor 4 20%
• Open-Angle Glaucoma 15%
• Western Blot 15%
• Immunohistochemistry 10%
• Ocular Hypertension 5%
• Intraocular Pressure 5%
• Protein Expression 5%
• Aqueous Humor Outflow 5%
• Prothrombin 5%
• Unfolded Protein Response 5%
• Translation Initiation 5%

Biochemistry, Genetics and Molecular Biology

• Endoplasmic Reticulum Stress 100%
• Activating Transcription Factor 4 40%
• Western Blot 30%
• Cell Lysate 20%
• Intraocular Pressure 10%
• Mouse Model 10%
• Aqueous Humor Outflow 10%
• Protein Expression 10%
• Eukaryotic Translation 10%
• Immunostaining 10%
• Initiation Factor 10%
• Unfolded Protein Response 10%